Antidiarrheal and bronchodilatory activities of olive extract

This study describes the antidiarrheal and airways-relaxant effects of the olive or Olea europea crude extract (Oe.Cr). Oe.Cr which tested positive for the presence of flavonoids and saponins, inhibited the castor oil-induced diarrhea in mice at the dose range of 100-300 mg/kg. When tested against c...

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Detalles Bibliográficos
Autores principales: Khan, Arif-ullah, Gilani, Anwarul-Hassan
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
antidiarrheal; bronchodilatory; olea europea, olive
Árboles
Extractos Vegetales
Antidiarreicos
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8093
http://www.latamjpharm.org/resumenes/30/1/LAJOP_30_1_1_1.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8093
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
antidiarrheal; bronchodilatory; olea europea, olive
Árboles
Extractos Vegetales
Antidiarreicos
spellingShingle Farmacia
antidiarrheal; bronchodilatory; olea europea, olive
Árboles
Extractos Vegetales
Antidiarreicos
Khan, Arif-ullah
Gilani, Anwarul-Hassan
Antidiarrheal and bronchodilatory activities of olive extract
topic_facet Farmacia
antidiarrheal; bronchodilatory; olea europea, olive
Árboles
Extractos Vegetales
Antidiarreicos
description This study describes the antidiarrheal and airways-relaxant effects of the olive or Olea europea crude extract (Oe.Cr). Oe.Cr which tested positive for the presence of flavonoids and saponins, inhibited the castor oil-induced diarrhea in mice at the dose range of 100-300 mg/kg. When tested against carbachol (CCh)-mediated bronchoconstriction in rats under anesthesia, Oe.Cr dose-dependently (30-300 mg/kg) suppressed the CCh (1 μmol/kg)-induced increase in the inspiratory pressure. In isolated guineapig trachea, Oe.Cr caused relaxation of both CCh (1μM) and high K+ (80 mM)-induced contractions, like that caused by verapamil, suggestive of Ca++ channel blockade. These results indicate that olive exhibit antidiarrheal, bronchodilatory and tracheo-relaxant activities.
format Articulo
Articulo
author Khan, Arif-ullah
Gilani, Anwarul-Hassan
author_facet Khan, Arif-ullah
Gilani, Anwarul-Hassan
author_sort Khan, Arif-ullah
title Antidiarrheal and bronchodilatory activities of olive extract
title_short Antidiarrheal and bronchodilatory activities of olive extract
title_full Antidiarrheal and bronchodilatory activities of olive extract
title_fullStr Antidiarrheal and bronchodilatory activities of olive extract
title_full_unstemmed Antidiarrheal and bronchodilatory activities of olive extract
title_sort antidiarrheal and bronchodilatory activities of olive extract
publishDate 2011
url http://sedici.unlp.edu.ar/handle/10915/8093
http://www.latamjpharm.org/resumenes/30/1/LAJOP_30_1_1_1.pdf
work_keys_str_mv AT khanarifullah antidiarrhealandbronchodilatoryactivitiesofoliveextract
AT gilanianwarulhassan antidiarrhealandbronchodilatoryactivitiesofoliveextract
bdutipo_str Repositorios
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