Validation of a spectrophotometric method in the visible region for the quantification of kojic acid in raw materials and products
A spectrophotometric method in the visible region was developed and validated for the quantification of kojic acid (KA) in raw materials and products. According to the validation results, this method yields linearity in the range of 5 and 50 μg/mL of KA (r = 0.99998), selectivity, suitable sensiti...
Guardado en:
| Autores principales: | , , , |
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| Formato: | Articulo Comunicacion |
| Lenguaje: | Inglés |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8092 http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_2_9.pdf |
| Aporte de: |
| id |
I19-R120-10915-8092 |
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| record_format |
dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Farmacia kojic acid; ferric chloride; spectrophotometry; validation of an analytical method |
| spellingShingle |
Farmacia kojic acid; ferric chloride; spectrophotometry; validation of an analytical method Piantavini, Mário S. Stremel, Dile P. Trindade, Ângela C.L.B. Pontarolo, Roberto Validation of a spectrophotometric method in the visible region for the quantification of kojic acid in raw materials and products |
| topic_facet |
Farmacia kojic acid; ferric chloride; spectrophotometry; validation of an analytical method |
| description |
A spectrophotometric method in the visible region was developed and validated for the quantification
of kojic acid (KA) in raw materials and products. According to the validation results, this
method yields linearity in the range of 5 and 50 μg/mL of KA (r = 0.99998), selectivity, suitable sensitivity,
precision (RSD 1.33 % and 1.21 % for intermediate precision and repeatability respectively), accuracy
(recovery near 100 %) and robustness (varying pH, temperature and reading time) were measured and
led to the validation of this method.These methods were tested and validated for various parameters according
to ICH guidelines and USP. |
| format |
Articulo Comunicacion |
| author |
Piantavini, Mário S. Stremel, Dile P. Trindade, Ângela C.L.B. Pontarolo, Roberto |
| author_facet |
Piantavini, Mário S. Stremel, Dile P. Trindade, Ângela C.L.B. Pontarolo, Roberto |
| author_sort |
Piantavini, Mário S. |
| title |
Validation of a spectrophotometric method in the visible region for the quantification of kojic acid in raw materials and products |
| title_short |
Validation of a spectrophotometric method in the visible region for the quantification of kojic acid in raw materials and products |
| title_full |
Validation of a spectrophotometric method in the visible region for the quantification of kojic acid in raw materials and products |
| title_fullStr |
Validation of a spectrophotometric method in the visible region for the quantification of kojic acid in raw materials and products |
| title_full_unstemmed |
Validation of a spectrophotometric method in the visible region for the quantification of kojic acid in raw materials and products |
| title_sort |
validation of a spectrophotometric method in the visible region for the quantification of kojic acid in raw materials and products |
| publishDate |
2010 |
| url |
http://sedici.unlp.edu.ar/handle/10915/8092 http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_2_9.pdf |
| work_keys_str_mv |
AT piantavinimarios validationofaspectrophotometricmethodinthevisibleregionforthequantificationofkojicacidinrawmaterialsandproducts AT stremeldilep validationofaspectrophotometricmethodinthevisibleregionforthequantificationofkojicacidinrawmaterialsandproducts AT trindadeangelaclb validationofaspectrophotometricmethodinthevisibleregionforthequantificationofkojicacidinrawmaterialsandproducts AT pontaroloroberto validationofaspectrophotometricmethodinthevisibleregionforthequantificationofkojicacidinrawmaterialsandproducts |
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Repositorios |
| _version_ |
1764820487879262209 |