Synthesis and pharmacological study of some novel thiazolidinones
A series of some novel thiazolidinones derivatives were synthesized and evaluated for their pharmacological activities. Thiazolidinones were synthesized from p-nitro aniline in four steps. First Schiff’s bases (V1- 8) were prepared by reacting the N4 -(4-nitrophenyl) thiazole-2,4-diamine (3) of p-ni...
Guardado en:
| Autores principales: | , , , , |
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| Formato: | Articulo Comunicacion |
| Lenguaje: | Inglés |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8086 http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_2_3.pdf |
| Aporte de: |
| id |
I19-R120-10915-8086 |
|---|---|
| record_format |
dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Farmacia analgesic; anti-inflammatory activity; p-nitro aniline; thiazolidinones analgesic; anti-inflammatory activity; p-nitro aniline; thiazolidinonesanalgesic; anti-inflammatory activity; p-nitro aniline; thiazolidinones |
| spellingShingle |
Farmacia analgesic; anti-inflammatory activity; p-nitro aniline; thiazolidinones analgesic; anti-inflammatory activity; p-nitro aniline; thiazolidinonesanalgesic; anti-inflammatory activity; p-nitro aniline; thiazolidinones Joshi, Vishal D. Bhat, Ishwar K. Jayaraman, R. Dahake, Akash P. Desai, Arvind R. Synthesis and pharmacological study of some novel thiazolidinones |
| topic_facet |
Farmacia analgesic; anti-inflammatory activity; p-nitro aniline; thiazolidinones analgesic; anti-inflammatory activity; p-nitro aniline; thiazolidinonesanalgesic; anti-inflammatory activity; p-nitro aniline; thiazolidinones |
| description |
A series of some novel thiazolidinones derivatives were synthesized and evaluated for their pharmacological activities. Thiazolidinones were synthesized from p-nitro aniline in four steps. First Schiff’s bases (V1- 8) were prepared by reacting the N4 -(4-nitrophenyl) thiazole-2,4-diamine (3) of p-nitro aniline derivatives with different aromatic aldehydes. Cyclocondensation of the Schiff’s bases with thioglycolic acid in presence of anhydrous zinc chloride resulted in the formation of the corresponding thiazolidinone (VD1-8) analogues. The structures of the newly synthesized compounds have been established on the basis of their spectral data. The synthesized selected compounds were evaluated for their anti-inflammatory and analgesic activity. |
| format |
Articulo Comunicacion |
| author |
Joshi, Vishal D. Bhat, Ishwar K. Jayaraman, R. Dahake, Akash P. Desai, Arvind R. |
| author_facet |
Joshi, Vishal D. Bhat, Ishwar K. Jayaraman, R. Dahake, Akash P. Desai, Arvind R. |
| author_sort |
Joshi, Vishal D. |
| title |
Synthesis and pharmacological study
of some novel thiazolidinones |
| title_short |
Synthesis and pharmacological study
of some novel thiazolidinones |
| title_full |
Synthesis and pharmacological study
of some novel thiazolidinones |
| title_fullStr |
Synthesis and pharmacological study
of some novel thiazolidinones |
| title_full_unstemmed |
Synthesis and pharmacological study
of some novel thiazolidinones |
| title_sort |
synthesis and pharmacological study
of some novel thiazolidinones |
| publishDate |
2010 |
| url |
http://sedici.unlp.edu.ar/handle/10915/8086 http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_2_3.pdf |
| work_keys_str_mv |
AT joshivishald synthesisandpharmacologicalstudyofsomenovelthiazolidinones AT bhatishwark synthesisandpharmacologicalstudyofsomenovelthiazolidinones AT jayaramanr synthesisandpharmacologicalstudyofsomenovelthiazolidinones AT dahakeakashp synthesisandpharmacologicalstudyofsomenovelthiazolidinones AT desaiarvindr synthesisandpharmacologicalstudyofsomenovelthiazolidinones |
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Repositorios |
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1764820487806910465 |