Toxicity study of a phytotherapic with Anemopaegma mirandum, Cola nitida, Passiflora alata, Paullinia cupana, Ptychopetalum olacoides and thiamin in rabbits

The phytotherapic formulation constituted by Anemopaegma mirandum (catuaba), Cola nitida (nóz de cola), Passiflora alata (maracujá), Paullinia cupana (guaraná), Ptychopetalum olacoides (marapuama) and thiamin chlorhydrate (Nerviton®) was investigated from the potential of toxicological effects when...

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Autores principales:	Mello, Joao Roberto Braga de, Mello, Fernanda B. de, Langeloh, Augusto
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2010
Materias:	Farmacia phytoterapic; anemopaegma mirandum; catuaba; cola nitida; guaraná; maracujá; marapuama; nóz de cola; passiflora alata; paullinia cupana; ptychopetalum olacoides; rabbits; thiamin chlorhydrate Plantas Medicinales Tiamina
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/8084 http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_2_1.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-8084
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia phytoterapic; anemopaegma mirandum; catuaba; cola nitida; guaraná; maracujá; marapuama; nóz de cola; passiflora alata; paullinia cupana; ptychopetalum olacoides; rabbits; thiamin chlorhydrate Plantas Medicinales Tiamina
spellingShingle	Farmacia phytoterapic; anemopaegma mirandum; catuaba; cola nitida; guaraná; maracujá; marapuama; nóz de cola; passiflora alata; paullinia cupana; ptychopetalum olacoides; rabbits; thiamin chlorhydrate Plantas Medicinales Tiamina Mello, Joao Roberto Braga de Mello, Fernanda B. de Langeloh, Augusto Toxicity study of a phytotherapic with <i>Anemopaegma mirandum</i>, <i>Cola nitida</i>, <i>Passiflora alata</i>, <i>Paullinia cupana</i>, <i>Ptychopetalum olacoides</i> and thiamin in rabbits
topic_facet	Farmacia phytoterapic; anemopaegma mirandum; catuaba; cola nitida; guaraná; maracujá; marapuama; nóz de cola; passiflora alata; paullinia cupana; ptychopetalum olacoides; rabbits; thiamin chlorhydrate Plantas Medicinales Tiamina
description	The phytotherapic formulation constituted by Anemopaegma mirandum (catuaba), Cola nitida (nóz de cola), Passiflora alata (maracujá), Paullinia cupana (guaraná), Ptychopetalum olacoides (marapuama) and thiamin chlorhydrate (Nerviton®) was investigated from the potential of toxicological effects when orally administered for 30 days to male and female New Zealand rabbits. The daily oral dose was ten times the prescribed dosage to humans. The general signs of toxicity, locomotion, behavior, respiratory rate and rhythm were evaluated. Body weight, food and water intake, rectal temperature, hematological and biochemical blood analysis, urinalysis, anatomopathological evaluation and visceral weight were measured. The results interpreted as a whole revealed the absence of toxicological effects to the phytotherapic studied when administered to New Zealand rabbits in a dose equivalent to 10 times the human dose and then can be considered relatively innocuous.
format	Articulo Comunicacion
author	Mello, Joao Roberto Braga de Mello, Fernanda B. de Langeloh, Augusto
author_facet	Mello, Joao Roberto Braga de Mello, Fernanda B. de Langeloh, Augusto
author_sort	Mello, Joao Roberto Braga de
title	Toxicity study of a phytotherapic with <i>Anemopaegma mirandum</i>, <i>Cola nitida</i>, <i>Passiflora alata</i>, <i>Paullinia cupana</i>, <i>Ptychopetalum olacoides</i> and thiamin in rabbits
title_short	Toxicity study of a phytotherapic with <i>Anemopaegma mirandum</i>, <i>Cola nitida</i>, <i>Passiflora alata</i>, <i>Paullinia cupana</i>, <i>Ptychopetalum olacoides</i> and thiamin in rabbits
title_full	Toxicity study of a phytotherapic with <i>Anemopaegma mirandum</i>, <i>Cola nitida</i>, <i>Passiflora alata</i>, <i>Paullinia cupana</i>, <i>Ptychopetalum olacoides</i> and thiamin in rabbits
title_fullStr	Toxicity study of a phytotherapic with <i>Anemopaegma mirandum</i>, <i>Cola nitida</i>, <i>Passiflora alata</i>, <i>Paullinia cupana</i>, <i>Ptychopetalum olacoides</i> and thiamin in rabbits
title_full_unstemmed	Toxicity study of a phytotherapic with <i>Anemopaegma mirandum</i>, <i>Cola nitida</i>, <i>Passiflora alata</i>, <i>Paullinia cupana</i>, <i>Ptychopetalum olacoides</i> and thiamin in rabbits
title_sort	toxicity study of a phytotherapic with <i>anemopaegma mirandum</i>, <i>cola nitida</i>, <i>passiflora alata</i>, <i>paullinia cupana</i>, <i>ptychopetalum olacoides</i> and thiamin in rabbits
publishDate	2010
url	http://sedici.unlp.edu.ar/handle/10915/8084 http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_2_1.pdf
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Toxicity study of a phytotherapic with <i>Anemopaegma mirandum</i>, <i>Cola nitida</i>, <i>Passiflora alata</i>, <i>Paullinia cupana</i>, <i>Ptychopetalum olacoides</i> and thiamin in rabbits

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