Osmotic and activity coefficients of aqueous solutions of the anesthetic drugs lidocaine-HCl and procaine-HCl at 298.15 K

Osmotic and activity coefficients were measured for aqueous solutions of Lidocaine-HCl and Procaine-HCl using the isopiestic method at 298.15 K. The results were fitted to the Pitzer equation and the parameters were calculated. A good correlation with the Pitzer model was found. The osmotic coeffici...

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Autores principales: Torres, Daniel R., Blanco, Luis H., Vargas, Edgar F., Martínez, Fleming
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
lidocaine-HCl; procaine-HCl; activity coefficient; isopiestic method; local anesthetics
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8060
http://www.latamjpharm.org/resumenes/29/7/LAJOP_29_7_2_7.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8060
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
lidocaine-HCl; procaine-HCl; activity coefficient; isopiestic method; local anesthetics
spellingShingle Farmacia
lidocaine-HCl; procaine-HCl; activity coefficient; isopiestic method; local anesthetics
Torres, Daniel R.
Blanco, Luis H.
Vargas, Edgar F.
Martínez, Fleming
Osmotic and activity coefficients of aqueous solutions of the anesthetic drugs lidocaine-HCl and procaine-HCl at 298.15 K
topic_facet Farmacia
lidocaine-HCl; procaine-HCl; activity coefficient; isopiestic method; local anesthetics
description Osmotic and activity coefficients were measured for aqueous solutions of Lidocaine-HCl and Procaine-HCl using the isopiestic method at 298.15 K. The results were fitted to the Pitzer equation and the parameters were calculated. A good correlation with the Pitzer model was found. The osmotic coefficients thus obtained were analyzed by comparing them with the Debye-Hückel limiting law. The results are discussed in terms of ion-solvent and ion-ion interactions.
format Articulo
Comunicacion
author Torres, Daniel R.
Blanco, Luis H.
Vargas, Edgar F.
Martínez, Fleming
author_facet Torres, Daniel R.
Blanco, Luis H.
Vargas, Edgar F.
Martínez, Fleming
author_sort Torres, Daniel R.
title Osmotic and activity coefficients of aqueous solutions of the anesthetic drugs lidocaine-HCl and procaine-HCl at 298.15 K
title_short Osmotic and activity coefficients of aqueous solutions of the anesthetic drugs lidocaine-HCl and procaine-HCl at 298.15 K
title_full Osmotic and activity coefficients of aqueous solutions of the anesthetic drugs lidocaine-HCl and procaine-HCl at 298.15 K
title_fullStr Osmotic and activity coefficients of aqueous solutions of the anesthetic drugs lidocaine-HCl and procaine-HCl at 298.15 K
title_full_unstemmed Osmotic and activity coefficients of aqueous solutions of the anesthetic drugs lidocaine-HCl and procaine-HCl at 298.15 K
title_sort osmotic and activity coefficients of aqueous solutions of the anesthetic drugs lidocaine-hcl and procaine-hcl at 298.15 k
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/8060
http://www.latamjpharm.org/resumenes/29/7/LAJOP_29_7_2_7.pdf
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