A quantitative method using one marker for simultaneous assay of steroidal saponins in rhizoma paridis

Current quality control patterns are limited to industrial application, for most the natural chemical reference substances are expensive and unavailable. Here in, quantitative analysis of multi-components with single marker (QAMS) method, is established and validated to simultaneously determine five...

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Detalles Bibliográficos
Autores principales: Ma, Chaoyi, Gao, Wenyuan, Man, Shuli, Gao, Ying, Huang, Luqi, Liu, Changxiao
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
quantitative analysis of multi-components by a single marker; relative correction factor; HPLC; steroidal saponins; rhizoma paridis
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8045
http://www.latamjpharm.org/resumenes/29/7/LAJOP_29_7_1_18.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8045
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
quantitative analysis of multi-components by a single marker; relative correction factor; HPLC; steroidal saponins; rhizoma paridis
spellingShingle Farmacia
quantitative analysis of multi-components by a single marker; relative correction factor; HPLC; steroidal saponins; rhizoma paridis
Ma, Chaoyi
Gao, Wenyuan
Man, Shuli
Gao, Ying
Huang, Luqi
Liu, Changxiao
A quantitative method using one marker for simultaneous assay of steroidal saponins in rhizoma paridis
topic_facet Farmacia
quantitative analysis of multi-components by a single marker; relative correction factor; HPLC; steroidal saponins; rhizoma paridis
description Current quality control patterns are limited to industrial application, for most the natural chemical reference substances are expensive and unavailable. Here in, quantitative analysis of multi-components with single marker (QAMS) method, is established and validated to simultaneously determine five steroidal saponins (Paris-VII, Paris-H, Paris-II, Dioscin , Paris-I) in Rhizoma Paridis. Using Paris-I as the contrast, the relative correction factors (RCF) of the other four steroidal saponins are determined by HPLC-UV. With in the linear ranges, the values of RCF of Paris-I to Paris-VII, Paris-H, Paris-II and Dioscin are 0.877, 1.087, 0.975 and 1.127, respectively. The RCF has a good reproducibility in various instruments, chromatographic columns (RSD = 0.88 % ~ 4.52 %). According to their RCF, five steroidal saponins are simultaneously determined in Rhizoma Paridis by one marker.
format Articulo
Articulo
author Ma, Chaoyi
Gao, Wenyuan
Man, Shuli
Gao, Ying
Huang, Luqi
Liu, Changxiao
author_facet Ma, Chaoyi
Gao, Wenyuan
Man, Shuli
Gao, Ying
Huang, Luqi
Liu, Changxiao
author_sort Ma, Chaoyi
title A quantitative method using one marker for simultaneous assay of steroidal saponins in rhizoma paridis
title_short A quantitative method using one marker for simultaneous assay of steroidal saponins in rhizoma paridis
title_full A quantitative method using one marker for simultaneous assay of steroidal saponins in rhizoma paridis
title_fullStr A quantitative method using one marker for simultaneous assay of steroidal saponins in rhizoma paridis
title_full_unstemmed A quantitative method using one marker for simultaneous assay of steroidal saponins in rhizoma paridis
title_sort quantitative method using one marker for simultaneous assay of steroidal saponins in rhizoma paridis
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/8045
http://www.latamjpharm.org/resumenes/29/7/LAJOP_29_7_1_18.pdf
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