Psychopharmacological activities of acorus calamus roots in rat and mice models

Acorus calamus (Araceae) is commonly known in India as sweet flag and has been used in traditional medicine as a remedy for pain, convulsion, inflammation, and ulcer. In the present work, the methanolic extract of Acorus calamus roots (MEAC) was assessed for different psychopharmacological activit...

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Autores principales: Rajangam, Jayaraman, Thiyagarajan, Anitha, Joshi, Vishal D., Palei, Narahari
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
Acorus calamus; methanol extract; psychopharmacological activities
Farmacología
Extractos de plantas
Evaluación de drogas
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8018
http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_2_3.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8018
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Acorus calamus; methanol extract; psychopharmacological activities
Farmacología
Extractos de plantas
Evaluación de drogas
spellingShingle Farmacia
Acorus calamus; methanol extract; psychopharmacological activities
Farmacología
Extractos de plantas
Evaluación de drogas
Rajangam, Jayaraman
Thiyagarajan, Anitha
Joshi, Vishal D.
Palei, Narahari
Psychopharmacological activities of acorus calamus roots in rat and mice models
topic_facet Farmacia
Acorus calamus; methanol extract; psychopharmacological activities
Farmacología
Extractos de plantas
Evaluación de drogas
description Acorus calamus (Araceae) is commonly known in India as sweet flag and has been used in traditional medicine as a remedy for pain, convulsion, inflammation, and ulcer. In the present work, the methanolic extract of Acorus calamus roots (MEAC) was assessed for different psychopharmacological activities in rats and mice by evaluation of general, exploratory behaviour, phenobarbitone sodium-induced sleeping time and muscle relaxant activity. The extract at doses 100 mg/kg and above exhibited a reduction in spontaneous activity and a decrease in exploratory behavioural pattern was observed. Also a significant reduction in muscle relaxant activity and potentiated phenobarbitone sodium-induced sleeping time in mice was noted in MEAC treated groups. From our study, the results indicates that MEAC appears to have effects on alteration in general behavior pattern, evident from the spontaneous activity, sound, touch and pain responses of the MEAC treated groups.
format Articulo
Comunicacion
author Rajangam, Jayaraman
Thiyagarajan, Anitha
Joshi, Vishal D.
Palei, Narahari
author_facet Rajangam, Jayaraman
Thiyagarajan, Anitha
Joshi, Vishal D.
Palei, Narahari
author_sort Rajangam, Jayaraman
title Psychopharmacological activities of acorus calamus roots in rat and mice models
title_short Psychopharmacological activities of acorus calamus roots in rat and mice models
title_full Psychopharmacological activities of acorus calamus roots in rat and mice models
title_fullStr Psychopharmacological activities of acorus calamus roots in rat and mice models
title_full_unstemmed Psychopharmacological activities of acorus calamus roots in rat and mice models
title_sort psychopharmacological activities of acorus calamus roots in rat and mice models
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/8018
http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_2_3.pdf
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AT joshivishald psychopharmacologicalactivitiesofacoruscalamusrootsinratandmicemodels
AT paleinarahari psychopharmacologicalactivitiesofacoruscalamusrootsinratandmicemodels
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