Topical formulation with Cordia verbenacea essential oil and glycolic acid

This study evaluated the effect of Cordia verbenacea essential oil (CV) and glycolic acid 70 % (GA), isolated and associated, on Wistar rats back skin. A base gel was added to 2 % of CV and/or 10 % of GA, thus forming 4 formulations: 1) GA + CV, 2) CV, 3) GA, and 4) gel base. All formulation had t...

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Detalles Bibliográficos
Autores principales:	Leonardi, Gislaine R., Rigon, Roberta B., Cavallini, Míriam Elias, Polacow, María L. O., Araújo, Marina R., Andreollo, Nelson A.
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2010
Materias:	Farmacia Cordia verbenacea; epidermis; fibroblasts; glycolic acid; leukocytes Farmacología Aceites Extractos de plantas
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/8017 http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_2_2.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-8017
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia Cordia verbenacea; epidermis; fibroblasts; glycolic acid; leukocytes Farmacología Aceites Extractos de plantas
spellingShingle	Farmacia Cordia verbenacea; epidermis; fibroblasts; glycolic acid; leukocytes Farmacología Aceites Extractos de plantas Leonardi, Gislaine R. Rigon, Roberta B. Cavallini, Míriam Elias Polacow, María L. O. Araújo, Marina R. Andreollo, Nelson A. Topical formulation with Cordia verbenacea essential oil and glycolic acid
topic_facet	Farmacia Cordia verbenacea; epidermis; fibroblasts; glycolic acid; leukocytes Farmacología Aceites Extractos de plantas
description	This study evaluated the effect of Cordia verbenacea essential oil (CV) and glycolic acid 70 % (GA), isolated and associated, on Wistar rats back skin. A base gel was added to 2 % of CV and/or 10 % of GA, thus forming 4 formulations: 1) GA + CV, 2) CV, 3) GA, and 4) gel base. All formulation had their final pH adjusted to 3,5 and were applied once daily, for 15 consecutive days, on 4 areas with 1 cm2, while another area without application (control). Statistical analysis of biopsies showed no difference in epidermis thickness and stratum corneum. Among fibroblast counts there was a statistical significance for groups exposed to the GA and to the association. Only in the group exposed to GAT there was significant difference in leukocytes number. The association of GA with CV proved favorable because it increased fibroblast counts without increasing leukocyte numbers, meaning inflammatory reaction may be reduced
format	Articulo Comunicacion
author	Leonardi, Gislaine R. Rigon, Roberta B. Cavallini, Míriam Elias Polacow, María L. O. Araújo, Marina R. Andreollo, Nelson A.
author_facet	Leonardi, Gislaine R. Rigon, Roberta B. Cavallini, Míriam Elias Polacow, María L. O. Araújo, Marina R. Andreollo, Nelson A.
author_sort	Leonardi, Gislaine R.
title	Topical formulation with Cordia verbenacea essential oil and glycolic acid
title_short	Topical formulation with Cordia verbenacea essential oil and glycolic acid
title_full	Topical formulation with Cordia verbenacea essential oil and glycolic acid
title_fullStr	Topical formulation with Cordia verbenacea essential oil and glycolic acid
title_full_unstemmed	Topical formulation with Cordia verbenacea essential oil and glycolic acid
title_sort	topical formulation with cordia verbenacea essential oil and glycolic acid
publishDate	2010
url	http://sedici.unlp.edu.ar/handle/10915/8017 http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_2_2.pdf
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Topical formulation with Cordia verbenacea essential oil and glycolic acid

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