Investigation of the anti-inflammatory and synergistic activities of bulbus Fritillariae ussuriensis and xuehua pear using acute inflammatory models

The combination of the bulb of Fritillaria ussuriensis Maxim. (Bulbus Fritillariae ussuriensis, BFU) and the fruit of Pyrus bretschneideri Rehd. (Xuehua pear, PBR), as folk medicine, is widely used in treatment with respiratory disease. In this study, three acute inflammatory models were used to est...

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Detalles Bibliográficos
Autores principales: Huang, Lijing, Gao, Wenyuan, Li, Xia, Man, Shuli, Zhang, Yanjun, Huang, Luqi, Liu, Changxiao
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
anti-inflammatory effect; bulbus fritillariae ussuriensis; fritillaria ussuriensis maxim; pyrus bretschneideri rehd.; synergistic activity; xuehua pear
Plantas medicinales
Enfermedades respiratorias
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8010
http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_1_15.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8010
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
anti-inflammatory effect; bulbus fritillariae ussuriensis; fritillaria ussuriensis maxim; pyrus bretschneideri rehd.; synergistic activity; xuehua pear
Farmacia
Plantas medicinales
Enfermedades respiratorias
spellingShingle Farmacia
anti-inflammatory effect; bulbus fritillariae ussuriensis; fritillaria ussuriensis maxim; pyrus bretschneideri rehd.; synergistic activity; xuehua pear
Farmacia
Plantas medicinales
Enfermedades respiratorias
Huang, Lijing
Gao, Wenyuan
Li, Xia
Man, Shuli
Zhang, Yanjun
Huang, Luqi
Liu, Changxiao
Investigation of the anti-inflammatory and synergistic activities of bulbus Fritillariae ussuriensis and xuehua pear using acute inflammatory models
topic_facet Farmacia
anti-inflammatory effect; bulbus fritillariae ussuriensis; fritillaria ussuriensis maxim; pyrus bretschneideri rehd.; synergistic activity; xuehua pear
Farmacia
Plantas medicinales
Enfermedades respiratorias
description The combination of the bulb of Fritillaria ussuriensis Maxim. (Bulbus Fritillariae ussuriensis, BFU) and the fruit of Pyrus bretschneideri Rehd. (Xuehua pear, PBR), as folk medicine, is widely used in treatment with respiratory disease. In this study, three acute inflammatory models were used to estimate the anti-inflammatory activities and cooperative interactions of them. The data were dealt with the Tallarida's improved contouring method and the Q value method to evaluate the cooperative interactions of BFU and PBR more directly. All the treated groups showed well preventive effects on xylene-induced mouse auricular edema, acetic acid-induced mouse vascular permeation and carrageenin-induced rat paw edema in a dose-dependent manner. Combination of BFU and PBR (CBP) exhibited a higher inhibitory effect than the additive effect of individuals. These results indicated that BFU and PBR both had good antiinflammatory effects and the combination of them had synergistic effects on acute inflammation, which may support and supplement the civilian utilization of Bulbus Fritillariae and Fructus Pyri in treatment with the respiratory tract diseases, just like pharyngitis, laryngitis, tonsillitis, etc.
format Articulo
Articulo
author Huang, Lijing
Gao, Wenyuan
Li, Xia
Man, Shuli
Zhang, Yanjun
Huang, Luqi
Liu, Changxiao
author_facet Huang, Lijing
Gao, Wenyuan
Li, Xia
Man, Shuli
Zhang, Yanjun
Huang, Luqi
Liu, Changxiao
author_sort Huang, Lijing
title Investigation of the anti-inflammatory and synergistic activities of bulbus Fritillariae ussuriensis and xuehua pear using acute inflammatory models
title_short Investigation of the anti-inflammatory and synergistic activities of bulbus Fritillariae ussuriensis and xuehua pear using acute inflammatory models
title_full Investigation of the anti-inflammatory and synergistic activities of bulbus Fritillariae ussuriensis and xuehua pear using acute inflammatory models
title_fullStr Investigation of the anti-inflammatory and synergistic activities of bulbus Fritillariae ussuriensis and xuehua pear using acute inflammatory models
title_full_unstemmed Investigation of the anti-inflammatory and synergistic activities of bulbus Fritillariae ussuriensis and xuehua pear using acute inflammatory models
title_sort investigation of the anti-inflammatory and synergistic activities of bulbus fritillariae ussuriensis and xuehua pear using acute inflammatory models
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/8010
http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_1_15.pdf
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