Simultaneous quantification of nine flavonoids in Ginkgo biloba extract tablets by HPLC-DAD

A new HPLC-DAD method has been developed and validated for the simultaneous analysis of nine flavonoids (rutin, myricetin, quercitrin, quercetin, luteolin, genistein, kaempferol, apigenin, and isorhamnetin) in Ginkgo biloba tablets. The analytes were separated on a kromasil C<sub>18</sub>...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Tang, Daoquan, Chen, Yonggang, Yang, Dongzhi, Gao, Yuanyuan, Tang, Anbang, Jiang, Xianglan, Yin, Xiaoxin
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
flavonoids; Ginkgo biloba tablet; high performance liquid chromatography; method validation; quantitative analysis
Farmacología
Extractos de plantas
Cromatografia líquida de alta eficiencia
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7996
http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_1_1.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-7996
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
flavonoids; Ginkgo biloba tablet; high performance liquid chromatography; method validation; quantitative analysis
Farmacología
Extractos de plantas
Cromatografia líquida de alta eficiencia
spellingShingle Farmacia
flavonoids; Ginkgo biloba tablet; high performance liquid chromatography; method validation; quantitative analysis
Farmacología
Extractos de plantas
Cromatografia líquida de alta eficiencia
Tang, Daoquan
Chen, Yonggang
Yang, Dongzhi
Gao, Yuanyuan
Tang, Anbang
Jiang, Xianglan
Yin, Xiaoxin
Simultaneous quantification of nine flavonoids in Ginkgo biloba extract tablets by HPLC-DAD
topic_facet Farmacia
flavonoids; Ginkgo biloba tablet; high performance liquid chromatography; method validation; quantitative analysis
Farmacología
Extractos de plantas
Cromatografia líquida de alta eficiencia
description A new HPLC-DAD method has been developed and validated for the simultaneous analysis of nine flavonoids (rutin, myricetin, quercitrin, quercetin, luteolin, genistein, kaempferol, apigenin, and isorhamnetin) in Ginkgo biloba tablets. The analytes were separated on a kromasil C<sub>18</sub> column and recorded at 254 nm. The greatest resolution was achieved with methanol-0.1 % formic acid gradient at a flow rate of 1.0 mL min<sup>-1</sup> For all the analytes, the correlation coefficients for all the calibration plots (R<sup>2</sup><0.999) showed good linearity over the range tested. The method was validated for repeatability, precision, stability, accuracy, selectivity, and robustness. The validated method has been successfully applied to simultaneous analysis of these active components in Ginkgo biloba tablets from different manufacturers.
format Articulo
Articulo
author Tang, Daoquan
Chen, Yonggang
Yang, Dongzhi
Gao, Yuanyuan
Tang, Anbang
Jiang, Xianglan
Yin, Xiaoxin
author_facet Tang, Daoquan
Chen, Yonggang
Yang, Dongzhi
Gao, Yuanyuan
Tang, Anbang
Jiang, Xianglan
Yin, Xiaoxin
author_sort Tang, Daoquan
title Simultaneous quantification of nine flavonoids in Ginkgo biloba extract tablets by HPLC-DAD
title_short Simultaneous quantification of nine flavonoids in Ginkgo biloba extract tablets by HPLC-DAD
title_full Simultaneous quantification of nine flavonoids in Ginkgo biloba extract tablets by HPLC-DAD
title_fullStr Simultaneous quantification of nine flavonoids in Ginkgo biloba extract tablets by HPLC-DAD
title_full_unstemmed Simultaneous quantification of nine flavonoids in Ginkgo biloba extract tablets by HPLC-DAD
title_sort simultaneous quantification of nine flavonoids in ginkgo biloba extract tablets by hplc-dad
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/7996
http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_1_1.pdf
work_keys_str_mv AT tangdaoquan simultaneousquantificationofnineflavonoidsinginkgobilobaextracttabletsbyhplcdad
AT chenyonggang simultaneousquantificationofnineflavonoidsinginkgobilobaextracttabletsbyhplcdad
AT yangdongzhi simultaneousquantificationofnineflavonoidsinginkgobilobaextracttabletsbyhplcdad
AT gaoyuanyuan simultaneousquantificationofnineflavonoidsinginkgobilobaextracttabletsbyhplcdad
AT tanganbang simultaneousquantificationofnineflavonoidsinginkgobilobaextracttabletsbyhplcdad
AT jiangxianglan simultaneousquantificationofnineflavonoidsinginkgobilobaextracttabletsbyhplcdad
AT yinxiaoxin simultaneousquantificationofnineflavonoidsinginkgobilobaextracttabletsbyhplcdad
bdutipo_str Repositorios
_version_ 1764820487364411394

Ejemplares similares