Antinociceptive activity of the leaf essential oil of Coleus aromaticus Benth

The present study was undertaken to evaluate the possible antinociceptive effect of Coleus aromaticus Benth oil. The pain sensitivity was assessed by the acetic acid induced writhing and hotplate models in mice. The essential oil exhibited a significant reduction in acetic acid induced writhing re...

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Autores principales: Pandey, Rishabh D., Singh, Akhilesh V., Pandey, Awanish, Tripathi, Poonam
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
Aceites esenciales
antinociception; Coleus aromaticus Benth; essential oil; writhing test; hotplate test
Farmacología
Plantas medicinales
Agentes anticonceptivos
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7987
http://www.latamjpharm.org/resumenes/29/5/LAJOP_29_5_2_5.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-7987
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Aceites esenciales
antinociception; Coleus aromaticus Benth; essential oil; writhing test; hotplate test
Farmacología
Plantas medicinales
Agentes anticonceptivos
spellingShingle Farmacia
Aceites esenciales
antinociception; Coleus aromaticus Benth; essential oil; writhing test; hotplate test
Farmacología
Plantas medicinales
Agentes anticonceptivos
Pandey, Rishabh D.
Singh, Akhilesh V.
Pandey, Awanish
Tripathi, Poonam
Antinociceptive activity of the leaf essential oil of Coleus aromaticus Benth
topic_facet Farmacia
Aceites esenciales
antinociception; Coleus aromaticus Benth; essential oil; writhing test; hotplate test
Farmacología
Plantas medicinales
Agentes anticonceptivos
description The present study was undertaken to evaluate the possible antinociceptive effect of Coleus aromaticus Benth oil. The pain sensitivity was assessed by the acetic acid induced writhing and hotplate models in mice. The essential oil exhibited a significant reduction in acetic acid induced writhing response, a dose dependent increase in reaction time against thermal pain and a moderate motor impairment at analgesic doses and significant reduction in endurance time at higher dose on rotarod apparatus. These experimental results suggest that essential oil (250 and 500 mg/kg) produced analgesic effect in mice and may be a candidate for the development of pharmacological agents used in the pain management.
format Articulo
Comunicacion
author Pandey, Rishabh D.
Singh, Akhilesh V.
Pandey, Awanish
Tripathi, Poonam
author_facet Pandey, Rishabh D.
Singh, Akhilesh V.
Pandey, Awanish
Tripathi, Poonam
author_sort Pandey, Rishabh D.
title Antinociceptive activity of the leaf essential oil of Coleus aromaticus Benth
title_short Antinociceptive activity of the leaf essential oil of Coleus aromaticus Benth
title_full Antinociceptive activity of the leaf essential oil of Coleus aromaticus Benth
title_fullStr Antinociceptive activity of the leaf essential oil of Coleus aromaticus Benth
title_full_unstemmed Antinociceptive activity of the leaf essential oil of Coleus aromaticus Benth
title_sort antinociceptive activity of the leaf essential oil of coleus aromaticus benth
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/7987
http://www.latamjpharm.org/resumenes/29/5/LAJOP_29_5_2_5.pdf
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