In vivo studies on the bronchodilatory and analgesic activities of Hyoscyamus niger and Aspalathus linearis

The present study describes the in vivo bronchodilatory and analgesic activities of the crude extract of Hyoscyamus niger (Hn.Cr) and Aspalathus linearis (Al.Cr), which tested positive for alkaloids, coumarins, flavonoids, sterols, tannins, terpenes and flavonoids, tannins, saponins respectively. Hn...

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Autores principales: Khan, Arif-ullah, Gilani, Anwarul-Hassan
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
Farmacología
Hyoscyamus niger; Aspalathus linearis; bronchodilation; analgesia
Extractos de plantas
Enfermedades bronquiales
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7981
http://www.latamjpharm.org/resumenes/29/5/LAJOP_29_5_1_20.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-7981
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Farmacología
Hyoscyamus niger; Aspalathus linearis; bronchodilation; analgesia
Extractos de plantas
Enfermedades bronquiales
spellingShingle Farmacia
Farmacología
Hyoscyamus niger; Aspalathus linearis; bronchodilation; analgesia
Extractos de plantas
Enfermedades bronquiales
Khan, Arif-ullah
Gilani, Anwarul-Hassan
In vivo studies on the bronchodilatory and analgesic activities of Hyoscyamus niger and Aspalathus linearis
topic_facet Farmacia
Farmacología
Hyoscyamus niger; Aspalathus linearis; bronchodilation; analgesia
Extractos de plantas
Enfermedades bronquiales
description The present study describes the in vivo bronchodilatory and analgesic activities of the crude extract of Hyoscyamus niger (Hn.Cr) and Aspalathus linearis (Al.Cr), which tested positive for alkaloids, coumarins, flavonoids, sterols, tannins, terpenes and flavonoids, tannins, saponins respectively. Hn.Cr (0.3-3.0 mg/kg) and Al.Cr (10-100 mg/kg) caused inhibition of the CCh (1 μmol/kg)-induced increase in the inspiratory pressure of anaesthetized rats. Hn.Cr and Al.Cr dose-dependently (50-100 mg/kg) reduced the numbers of acetic acid-mediated writhes in mice. These results indicate that Hyoscyamus niger and Aspalathus linearis exhibit airways-relaxant and anti-nociceptive effects, hence justifying their medicinal use in asthma and pain.
format Articulo
Articulo
author Khan, Arif-ullah
Gilani, Anwarul-Hassan
author_facet Khan, Arif-ullah
Gilani, Anwarul-Hassan
author_sort Khan, Arif-ullah
title In vivo studies on the bronchodilatory and analgesic activities of Hyoscyamus niger and Aspalathus linearis
title_short In vivo studies on the bronchodilatory and analgesic activities of Hyoscyamus niger and Aspalathus linearis
title_full In vivo studies on the bronchodilatory and analgesic activities of Hyoscyamus niger and Aspalathus linearis
title_fullStr In vivo studies on the bronchodilatory and analgesic activities of Hyoscyamus niger and Aspalathus linearis
title_full_unstemmed In vivo studies on the bronchodilatory and analgesic activities of Hyoscyamus niger and Aspalathus linearis
title_sort in vivo studies on the bronchodilatory and analgesic activities of hyoscyamus niger and aspalathus linearis
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/7981
http://www.latamjpharm.org/resumenes/29/5/LAJOP_29_5_1_20.pdf
work_keys_str_mv AT khanarifullah invivostudiesonthebronchodilatoryandanalgesicactivitiesofhyoscyamusnigerandaspalathuslinearis
AT gilanianwarulhassan invivostudiesonthebronchodilatoryandanalgesicactivitiesofhyoscyamusnigerandaspalathuslinearis
bdutipo_str Repositorios
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