A new antibacterial pyridinoside from a Streptomyces species

A new compound, 8-propionate-2-β-(D+)-glucosyl-9,10-pyranopyridine, was isolated from the chloroform extract of a Streptomyces species. The structure of the compound was confirmed by spectroscopic techniques including UV, IR, HR-ESI-MS, 1H-NMR, 13C-NMR, 1H-1H COSY and HMBC (long range coupling) spec...

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Detalles Bibliográficos
Autores principales:	Barman, Ranjan K., Gafur, Mohammad A., Rahman, Bytul M., Khondkar, Proma
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2010
Materias:	Farmacia antibacterial activity; 8-propionate-2-β-(D+)-glucosyl-9;10-pyranopyridine; Streptomyces species Farmacología Bacterias Bacterias gram-positivas
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/7949 http://www.latamjpharm.org/resumenes/29/4/LAJOP_29_4_1_12.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia antibacterial activity; 8-propionate-2-β-(D+)-glucosyl-9;10-pyranopyridine; Streptomyces species Farmacología Bacterias Bacterias gram-positivas
spellingShingle	Farmacia antibacterial activity; 8-propionate-2-β-(D+)-glucosyl-9;10-pyranopyridine; Streptomyces species Farmacología Bacterias Bacterias gram-positivas Barman, Ranjan K. Gafur, Mohammad A. Rahman, Bytul M. Khondkar, Proma A new antibacterial pyridinoside from a Streptomyces species
topic_facet	Farmacia antibacterial activity; 8-propionate-2-β-(D+)-glucosyl-9;10-pyranopyridine; Streptomyces species Farmacología Bacterias Bacterias gram-positivas
description	A new compound, 8-propionate-2-β-(D+)-glucosyl-9,10-pyranopyridine, was isolated from the chloroform extract of a Streptomyces species. The structure of the compound was confirmed by spectroscopic techniques including UV, IR, HR-ESI-MS, 1H-NMR, 13C-NMR, 1H-1H COSY and HMBC (long range coupling) spectra. The compound showed significant antibacterial activity against Gram-positive bacteria. The minimum inhibitory concentrations (MIC) of the isolated compound against Bacillus megaterium, Streptococcus β-haemolyticus, Bacillus subtilis, Escherichia coli, Salmonella typhi and Shigella dysenteriae were found to be 0.16, 0.08, 0.08, 0.04, 0.08 and 0.08 μM, respectively.
format	Articulo Articulo
author	Barman, Ranjan K. Gafur, Mohammad A. Rahman, Bytul M. Khondkar, Proma
author_facet	Barman, Ranjan K. Gafur, Mohammad A. Rahman, Bytul M. Khondkar, Proma
author_sort	Barman, Ranjan K.
title	A new antibacterial pyridinoside from a Streptomyces species
title_short	A new antibacterial pyridinoside from a Streptomyces species
title_full	A new antibacterial pyridinoside from a Streptomyces species
title_fullStr	A new antibacterial pyridinoside from a Streptomyces species
title_full_unstemmed	A new antibacterial pyridinoside from a Streptomyces species
title_sort	new antibacterial pyridinoside from a streptomyces species
publishDate	2010
url	http://sedici.unlp.edu.ar/handle/10915/7949 http://www.latamjpharm.org/resumenes/29/4/LAJOP_29_4_1_12.pdf
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bdutipo_str	Repositorios
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A new antibacterial pyridinoside from a Streptomyces species

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