Hepatoprotective fraction from aerial parts of Delonix regia

The present study deals with the amelioration by Delonix regia aerial parts extract against hepatotoxicity induced by carbon tetrachloride (CCl4), which was evaluated in terms of serum marker enzymes like aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, albumine, total...

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Detalles Bibliográficos
Autores principales:	Ahmed, Jameel, Nirmal, Sunil A., Dhasade, Vipul V., Mandal, Subhash C.
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2010
Materias:	Farmacia AST; ALT; Delonix regia; hepatoprotective; silymarin Farmacología Plantas medicinales Botánica
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/7937 http://www.latamjpharm.org/resumenes/29/3/LAJOP_29_3_2_7.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-7937
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia AST; ALT; Delonix regia; hepatoprotective; silymarin Farmacología Plantas medicinales Botánica
spellingShingle	Farmacia AST; ALT; Delonix regia; hepatoprotective; silymarin Farmacología Plantas medicinales Botánica Ahmed, Jameel Nirmal, Sunil A. Dhasade, Vipul V. Mandal, Subhash C. Hepatoprotective fraction from aerial parts of Delonix regia
topic_facet	Farmacia AST; ALT; Delonix regia; hepatoprotective; silymarin Farmacología Plantas medicinales Botánica
description	The present study deals with the amelioration by Delonix regia aerial parts extract against hepatotoxicity induced by carbon tetrachloride (CCl4), which was evaluated in terms of serum marker enzymes like aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, albumine, total protein, direct bilirubine and total bilirubine. These biochemical parameters were alter by the single dose of CCl4 (2 ml/kg, p.o.). Pretreatment with D. regia extracts prior to administration of CCl4, at the dose of 400 mg/kg p.o. per day for 7 days, significantly restored all the serum and liver tissue parameters near to the normal levels. Silymarine was used as reference standard. Amongst all the fractions, ethyl acetate fraction showed best protective potential of D. regia aerial parts against hepatotoxicity.
format	Articulo Comunicacion
author	Ahmed, Jameel Nirmal, Sunil A. Dhasade, Vipul V. Mandal, Subhash C.
author_facet	Ahmed, Jameel Nirmal, Sunil A. Dhasade, Vipul V. Mandal, Subhash C.
author_sort	Ahmed, Jameel
title	Hepatoprotective fraction from aerial parts of Delonix regia
title_short	Hepatoprotective fraction from aerial parts of Delonix regia
title_full	Hepatoprotective fraction from aerial parts of Delonix regia
title_fullStr	Hepatoprotective fraction from aerial parts of Delonix regia
title_full_unstemmed	Hepatoprotective fraction from aerial parts of Delonix regia
title_sort	hepatoprotective fraction from aerial parts of delonix regia
publishDate	2010
url	http://sedici.unlp.edu.ar/handle/10915/7937 http://www.latamjpharm.org/resumenes/29/3/LAJOP_29_3_2_7.pdf
work_keys_str_mv	AT ahmedjameel hepatoprotectivefractionfromaerialpartsofdelonixregia AT nirmalsunila hepatoprotectivefractionfromaerialpartsofdelonixregia AT dhasadevipulv hepatoprotectivefractionfromaerialpartsofdelonixregia AT mandalsubhashc hepatoprotectivefractionfromaerialpartsofdelonixregia
bdutipo_str	Repositorios
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Hepatoprotective fraction from aerial parts of Delonix regia

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