Preclinical study of the interference of different nutritional diets on the anti-inflammatory and analgesic actions of etoricoxib

The aim of this research was to evaluate the interference of the association of different types of nutritional diet in the anti-inflammatory and analgesic activities of etoricoxib in in vivo models. The following assays were used: a) Rat paw edema induced by carrageenan; b) Induction of the granulom...

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Detalles Bibliográficos
Autores principales:	Bianchetti, Erica S., Costa Dos Santos, Kelem, Perazzo, Fábio F., Carvalho, José C. T.
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2010
Materias:	Farmacia non-steroidal anti-inflammatory drug; Cox-2 inhibitors, etoricoxib; interaction with nutritional diets Farmacología Medicamentos Dieta Nutrición
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/7896 http://www.latamjpharm.org/resumenes/29/2/LAJOP_29_2_1_8.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-7896
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institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia non-steroidal anti-inflammatory drug; Cox-2 inhibitors, etoricoxib; interaction with nutritional diets Farmacología Medicamentos Dieta Nutrición
spellingShingle	Farmacia non-steroidal anti-inflammatory drug; Cox-2 inhibitors, etoricoxib; interaction with nutritional diets Farmacología Medicamentos Dieta Nutrición Bianchetti, Erica S. Costa Dos Santos, Kelem Perazzo, Fábio F. Carvalho, José C. T. Preclinical study of the interference of different nutritional diets on the anti-inflammatory and analgesic actions of etoricoxib
topic_facet	Farmacia non-steroidal anti-inflammatory drug; Cox-2 inhibitors, etoricoxib; interaction with nutritional diets Farmacología Medicamentos Dieta Nutrición
description	The aim of this research was to evaluate the interference of the association of different types of nutritional diet in the anti-inflammatory and analgesic activities of etoricoxib in in vivo models. The following assays were used: a) Rat paw edema induced by carrageenan; b) Induction of the granulomatous tissue by cotton pellet; c) Dermatitis induced by croton oil; d) Vascular permeability by histamine in rats; e) Writhing test by acetic acid in mice; f) Formalin test in mice and; g) Stress-induced gastric lesions. The association of etoricoxib with the different types of diet did not alter the anti-inflammatory effect in the assays employed, but potentialized the analgesic effect, particularly when associated with hyperproteic diet for peripheral pain and hyperglucidic diet for central pain. The association of etoricoxib with hyperglucidic diet decreased the gastric lesion rate.
format	Articulo Articulo
author	Bianchetti, Erica S. Costa Dos Santos, Kelem Perazzo, Fábio F. Carvalho, José C. T.
author_facet	Bianchetti, Erica S. Costa Dos Santos, Kelem Perazzo, Fábio F. Carvalho, José C. T.
author_sort	Bianchetti, Erica S.
title	Preclinical study of the interference of different nutritional diets on the anti-inflammatory and analgesic actions of etoricoxib
title_short	Preclinical study of the interference of different nutritional diets on the anti-inflammatory and analgesic actions of etoricoxib
title_full	Preclinical study of the interference of different nutritional diets on the anti-inflammatory and analgesic actions of etoricoxib
title_fullStr	Preclinical study of the interference of different nutritional diets on the anti-inflammatory and analgesic actions of etoricoxib
title_full_unstemmed	Preclinical study of the interference of different nutritional diets on the anti-inflammatory and analgesic actions of etoricoxib
title_sort	preclinical study of the interference of different nutritional diets on the anti-inflammatory and analgesic actions of etoricoxib
publishDate	2010
url	http://sedici.unlp.edu.ar/handle/10915/7896 http://www.latamjpharm.org/resumenes/29/2/LAJOP_29_2_1_8.pdf
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Preclinical study of the interference of different nutritional diets on the anti-inflammatory and analgesic actions of etoricoxib

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