Antimutagenic effect of Phyllanthus orbicularis against γ-radiation

The present work evaluated the protective effect of aqueous extract of Phyllanthus orbicularis against the mutagenicity of γ-radiation. The extract activity was determined in pre- and post-treatment procedures using Salmonella reversion assay. In either case, the plant extract protected bacterial ce...

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Autores principales: Alonso, Alena, Fuentes, Jorge L., Sánchez Lamar, Angel, Llagostera, Montserrat
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
Farmacología
Extractos de plantas
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7886
http://www.latamjpharm.org/trabajos/29/1/LAJOP_29_1_2_8_67U1235665.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-7886
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Farmacología
Extractos de plantas
spellingShingle Farmacia
Farmacología
Extractos de plantas
Alonso, Alena
Fuentes, Jorge L.
Sánchez Lamar, Angel
Llagostera, Montserrat
Antimutagenic effect of Phyllanthus orbicularis against γ-radiation
topic_facet Farmacia
Farmacología
Extractos de plantas
description The present work evaluated the protective effect of aqueous extract of Phyllanthus orbicularis against the mutagenicity of γ-radiation. The extract activity was determined in pre- and post-treatment procedures using Salmonella reversion assay. In either case, the plant extract protected bacterial cells against the mutations induced by γ-radiation, suggesting that it contains antimutagenic compounds which confer protection by at least two different mechanisms: i) as antioxidants targeting the oxidative mutagens induced by γ-radiation and ii) by modulation of the cellular repair enzymes acting on damaged DNA. The results are discussed in relation to the chemopreventive and radioprotective potential of P. orbicularis.
format Articulo
Comunicacion
author Alonso, Alena
Fuentes, Jorge L.
Sánchez Lamar, Angel
Llagostera, Montserrat
author_facet Alonso, Alena
Fuentes, Jorge L.
Sánchez Lamar, Angel
Llagostera, Montserrat
author_sort Alonso, Alena
title Antimutagenic effect of Phyllanthus orbicularis against γ-radiation
title_short Antimutagenic effect of Phyllanthus orbicularis against γ-radiation
title_full Antimutagenic effect of Phyllanthus orbicularis against γ-radiation
title_fullStr Antimutagenic effect of Phyllanthus orbicularis against γ-radiation
title_full_unstemmed Antimutagenic effect of Phyllanthus orbicularis against γ-radiation
title_sort antimutagenic effect of phyllanthus orbicularis against γ-radiation
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/7886
http://www.latamjpharm.org/trabajos/29/1/LAJOP_29_1_2_8_67U1235665.pdf
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AT fuentesjorgel antimutageniceffectofphyllanthusorbicularisagainstgradiation
AT sanchezlamarangel antimutageniceffectofphyllanthusorbicularisagainstgradiation
AT llagosteramontserrat antimutageniceffectofphyllanthusorbicularisagainstgradiation
bdutipo_str Repositorios
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