Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control

We compared the kinetic behaviour of tylosin administered to beehives by dusting or paper-pack placement through three treatment protocols (D, PP, CONTROL). D (dusting): tylosin, divided in four portions, was sprinkled over the ends of the hives' top bars weekly for four weeks (n=3); PP (paper-...

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Autores principales: Reynaldi, Francisco José, Albo, Graciela Noemí, Avellaneda, Elisa, Rule, Roberto
Formato: Articulo
Lenguaje:Inglés
Publicado: 2017
Materias:
Ciencias Veterinarias
american foulbrood
beehives
kinetics
tylosin
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/78149
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-78149
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
american foulbrood
beehives
kinetics
tylosin
spellingShingle Ciencias Veterinarias
american foulbrood
beehives
kinetics
tylosin
Reynaldi, Francisco José
Albo, Graciela Noemí
Avellaneda, Elisa
Rule, Roberto
Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
topic_facet Ciencias Veterinarias
american foulbrood
beehives
kinetics
tylosin
description We compared the kinetic behaviour of tylosin administered to beehives by dusting or paper-pack placement through three treatment protocols (D, PP, CONTROL). D (dusting): tylosin, divided in four portions, was sprinkled over the ends of the hives' top bars weekly for four weeks (n=3); PP (paper-pack placement): tylosin in paper packs was administered at two-week intervals (n=3); CONTROL (control): the hives were left untreated (n=3). In every inspection, from each of the nine hives, fifty young (2-day-old) larvae were sampled for drug analysis. The concentration of tylosin in the young larvae was determined by a microbiological assay with Geobacillus stearothermophilus ATCC 12980 as test organism. The (mean±SD) maximum concentration (Cmax) for D was 136.0±194.0 and for PP – 144.0±187.4 μg/mL; the time to reach Cmax (tmax) was 1.5±0.9 h for D and 1.8 ± 1.8 h for PP. The area under the tylosin behaviour kinetics curve between 0–1392 h with D was 308.7±185.2 and with PP: 326.4±141.0 μg/h/mL, indicating no statistical difference between the treatments (P>0.05). The shorter duration of paper-pack-administered tylosin observed in the larvae implied a lower risk of antibiotic residues in the resulting honey.
format Articulo
Articulo
author Reynaldi, Francisco José
Albo, Graciela Noemí
Avellaneda, Elisa
Rule, Roberto
author_facet Reynaldi, Francisco José
Albo, Graciela Noemí
Avellaneda, Elisa
Rule, Roberto
author_sort Reynaldi, Francisco José
title Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
title_short Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
title_full Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
title_fullStr Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
title_full_unstemmed Evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
title_sort evaluation of kinetic behaviour of two preparations of tylosin administered in beehives for american foulbrood control
publishDate 2017
url http://sedici.unlp.edu.ar/handle/10915/78149
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