Validation of an HPLC method for quantitative determination of benzocaine in PHBV-microparticles and PLA-nanoparticles

Benzocaine (BZC) is an ester-type local anesthetic used mainly in topical, dermal and mucosal formulations. The present work consists of the development and validation of analytical methodology for evaluation of benzocaine content in the micro and nanoparticles produced by biodegradable polymers (po...

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Autores principales: Grillo, Renato, S. de Melo, Nathalie F., Araújo, Daniele R. de, Paula, Eneida de, Dias Filho, Newton L., Rosa, André H., Fraceto, Leonardo F.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2009
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7774
http://www.latamjpharm.org/trabajos/28/3/LAJOP_28_3_1_10_662Q8GBZMX.pdf
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