Oil-based nanoparticles containing alternative vegetable oils (grape seed oil and almond kernel oil): preparation and characterization

The use of two alternative vegetable oils (grape seed oil and almond kernel oil) to prepare nanoparticulated delivery systems (nanocapsules and nanoemulsions) for active substances was evaluated. They were prepared by interfacial deposition of preformed polymer (poly-ε-caprolactone) or spontaneous e...

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Detalles Bibliográficos
Autores principales: Almeida, Juliana S., Jezur, Luciane, Fontana, Marcia C., Paese, Karina, Silva, Cristiane B., Pohlmann, Adriana Raffin, Guterres, Sílvia Stanisçuaski, Beck, Ruy Carlos Ruver
Formato: Articulo
Lenguaje:Inglés
Publicado: 2009
Materias:
Farmacia
Preparaciones Farmacéuticas
aceite vegetal
almond kernel oil; grape seed oil; nanoparticles
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7742
http://www.latamjpharm.org/trabajos/28/2/LAJOP_28_2_1_1_599ZY133S8.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-7742
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Preparaciones Farmacéuticas
aceite vegetal
almond kernel oil; grape seed oil; nanoparticles
spellingShingle Farmacia
Preparaciones Farmacéuticas
aceite vegetal
almond kernel oil; grape seed oil; nanoparticles
Almeida, Juliana S.
Jezur, Luciane
Fontana, Marcia C.
Paese, Karina
Silva, Cristiane B.
Pohlmann, Adriana Raffin
Guterres, Sílvia Stanisçuaski
Beck, Ruy Carlos Ruver
Oil-based nanoparticles containing alternative vegetable oils (grape seed oil and almond kernel oil): preparation and characterization
topic_facet Farmacia
Preparaciones Farmacéuticas
aceite vegetal
almond kernel oil; grape seed oil; nanoparticles
description The use of two alternative vegetable oils (grape seed oil and almond kernel oil) to prepare nanoparticulated delivery systems (nanocapsules and nanoemulsions) for active substances was evaluated. They were prepared by interfacial deposition of preformed polymer (poly-ε-caprolactone) or spontaneous emulsification, respectively. All formulations presented nanometric size, polydispersity index below 0.30, negative zeta potential and spherical-shaped particles. Benzophenone-3, as a model substance was efficiently entrapped in these systems, independent on the type of oily phase. Its association did not alter significantly the physicochemical properties of the nanoparticle dispersions, which remained adequate until 6 months of storage. Nanocapsules and nanoemulsions prepared with both vegetable oils were suitable to delay benzophenone-3 photodegradation under UV radiation.
format Articulo
Articulo
author Almeida, Juliana S.
Jezur, Luciane
Fontana, Marcia C.
Paese, Karina
Silva, Cristiane B.
Pohlmann, Adriana Raffin
Guterres, Sílvia Stanisçuaski
Beck, Ruy Carlos Ruver
author_facet Almeida, Juliana S.
Jezur, Luciane
Fontana, Marcia C.
Paese, Karina
Silva, Cristiane B.
Pohlmann, Adriana Raffin
Guterres, Sílvia Stanisçuaski
Beck, Ruy Carlos Ruver
author_sort Almeida, Juliana S.
title Oil-based nanoparticles containing alternative vegetable oils (grape seed oil and almond kernel oil): preparation and characterization
title_short Oil-based nanoparticles containing alternative vegetable oils (grape seed oil and almond kernel oil): preparation and characterization
title_full Oil-based nanoparticles containing alternative vegetable oils (grape seed oil and almond kernel oil): preparation and characterization
title_fullStr Oil-based nanoparticles containing alternative vegetable oils (grape seed oil and almond kernel oil): preparation and characterization
title_full_unstemmed Oil-based nanoparticles containing alternative vegetable oils (grape seed oil and almond kernel oil): preparation and characterization
title_sort oil-based nanoparticles containing alternative vegetable oils (grape seed oil and almond kernel oil): preparation and characterization
publishDate 2009
url http://sedici.unlp.edu.ar/handle/10915/7742
http://www.latamjpharm.org/trabajos/28/2/LAJOP_28_2_1_1_599ZY133S8.pdf
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