Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia

The plant Jatropha pandurifolia (Euphorbiaceae) has ethnopharmacological reputation of being used as a healing agent in Bangladesh. In this study, preliminary screenings were conducted to look at the antimicrobial susceptibility and cytotoxicity of the plant extract. The n-hexane extract of the plan...

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Autores principales:	Akhter, Afsana, Rahman, Mohammad S., Ahsan, Monira
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2008
Materias:	Farmacia antimicrobial; brine shrimp lethality bioassay; cytotoxicity; euphorbiaceae; Jatropha pandurifolia Farmacología Plantas medicinales Test de Citotoxicidad
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/7713 http://www.latamjpharm.org/trabajos/27/6/LAJOP_27_6_2_6_IYD0ZJ2048.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-7713
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia antimicrobial; brine shrimp lethality bioassay; cytotoxicity; euphorbiaceae; Jatropha pandurifolia Farmacología Plantas medicinales Test de Citotoxicidad
spellingShingle	Farmacia antimicrobial; brine shrimp lethality bioassay; cytotoxicity; euphorbiaceae; Jatropha pandurifolia Farmacología Plantas medicinales Test de Citotoxicidad Akhter, Afsana Rahman, Mohammad S. Ahsan, Monira Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
topic_facet	Farmacia antimicrobial; brine shrimp lethality bioassay; cytotoxicity; euphorbiaceae; Jatropha pandurifolia Farmacología Plantas medicinales Test de Citotoxicidad
description	The plant Jatropha pandurifolia (Euphorbiaceae) has ethnopharmacological reputation of being used as a healing agent in Bangladesh. In this study, preliminary screenings were conducted to look at the antimicrobial susceptibility and cytotoxicity of the plant extract. The n-hexane extract of the plant was subjected to screening for inhibition of microbial growth by the disc diffusion method and the average zone of inhibition was found 12-21 mm at a concentration of 500 μg/disc. The extract was also subjected to brine shrimp lethality bioassay for primary cytotoxicity evaluation and it revealed significant cytotoxicity with LC50 of 4.67 μg/ml. This is the first report of the antimicrobial activity and cytotoxicity of J. pandurifolia.
format	Articulo Comunicacion
author	Akhter, Afsana Rahman, Mohammad S. Ahsan, Monira
author_facet	Akhter, Afsana Rahman, Mohammad S. Ahsan, Monira
author_sort	Akhter, Afsana
title	Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
title_short	Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
title_full	Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
title_fullStr	Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
title_full_unstemmed	Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
title_sort	preliminary antimicrobial and cytotoxic activities of n-hexane extract of jatropha pandurifolia
publishDate	2008
url	http://sedici.unlp.edu.ar/handle/10915/7713 http://www.latamjpharm.org/trabajos/27/6/LAJOP_27_6_2_6_IYD0ZJ2048.pdf
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bdutipo_str	Repositorios
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Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia

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