Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia

The plant Jatropha pandurifolia (Euphorbiaceae) has ethnopharmacological reputation of being used as a healing agent in Bangladesh. In this study, preliminary screenings were conducted to look at the antimicrobial susceptibility and cytotoxicity of the plant extract. The n-hexane extract of the plan...

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Detalles Bibliográficos
Autores principales: Akhter, Afsana, Rahman, Mohammad S., Ahsan, Monira
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2008
Materias:
Farmacia
antimicrobial; brine shrimp lethality bioassay; cytotoxicity; euphorbiaceae; Jatropha pandurifolia
Farmacología
Plantas medicinales
Test de Citotoxicidad
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7713
http://www.latamjpharm.org/trabajos/27/6/LAJOP_27_6_2_6_IYD0ZJ2048.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-7713
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
antimicrobial; brine shrimp lethality bioassay; cytotoxicity; euphorbiaceae; Jatropha pandurifolia
Farmacología
Plantas medicinales
Test de Citotoxicidad
spellingShingle Farmacia
antimicrobial; brine shrimp lethality bioassay; cytotoxicity; euphorbiaceae; Jatropha pandurifolia
Farmacología
Plantas medicinales
Test de Citotoxicidad
Akhter, Afsana
Rahman, Mohammad S.
Ahsan, Monira
Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
topic_facet Farmacia
antimicrobial; brine shrimp lethality bioassay; cytotoxicity; euphorbiaceae; Jatropha pandurifolia
Farmacología
Plantas medicinales
Test de Citotoxicidad
description The plant Jatropha pandurifolia (Euphorbiaceae) has ethnopharmacological reputation of being used as a healing agent in Bangladesh. In this study, preliminary screenings were conducted to look at the antimicrobial susceptibility and cytotoxicity of the plant extract. The n-hexane extract of the plant was subjected to screening for inhibition of microbial growth by the disc diffusion method and the average zone of inhibition was found 12-21 mm at a concentration of 500 μg/disc. The extract was also subjected to brine shrimp lethality bioassay for primary cytotoxicity evaluation and it revealed significant cytotoxicity with LC50 of 4.67 μg/ml. This is the first report of the antimicrobial activity and cytotoxicity of J. pandurifolia.
format Articulo
Comunicacion
author Akhter, Afsana
Rahman, Mohammad S.
Ahsan, Monira
author_facet Akhter, Afsana
Rahman, Mohammad S.
Ahsan, Monira
author_sort Akhter, Afsana
title Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
title_short Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
title_full Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
title_fullStr Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
title_full_unstemmed Preliminary antimicrobial and cytotoxic activities of n-Hexane extract of Jatropha pandurifolia
title_sort preliminary antimicrobial and cytotoxic activities of n-hexane extract of jatropha pandurifolia
publishDate 2008
url http://sedici.unlp.edu.ar/handle/10915/7713
http://www.latamjpharm.org/trabajos/27/6/LAJOP_27_6_2_6_IYD0ZJ2048.pdf
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