Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers

Alu insertions, INDELs, and SNPs in the X chromosome can be useful not only for revealing relationships among populations but also for identification purposes. We present data of 10 Alu insertions, 5 INDELs, and 15 SNPs of X-chromosome from three Argentinian north-east cities in order to gain insigh...

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Autores principales: Di Santo Meztler, Gabriela Paula, Palacio, Santiago del, Esteban, María E., Armoa, Isaías, Argüelles, Carina Francisca, Catanesi, Cecilia Inés
Formato: Articulo
Lenguaje:Inglés
Publicado: 2018
Materias:
Ciencias Exactas
Argentina
Genética
polymorphism, X chromosome, genetic variation, Alus, INDELs, SNPs, Argentina
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/67519
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-67519
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Exactas
Argentina
Genética
polymorphism, X chromosome, genetic variation, Alus, INDELs, SNPs, Argentina
spellingShingle Ciencias Exactas
Argentina
Genética
polymorphism, X chromosome, genetic variation, Alus, INDELs, SNPs, Argentina
Di Santo Meztler, Gabriela Paula
Palacio, Santiago del
Esteban, María E.
Armoa, Isaías
Argüelles, Carina Francisca
Catanesi, Cecilia Inés
Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
topic_facet Ciencias Exactas
Argentina
Genética
polymorphism, X chromosome, genetic variation, Alus, INDELs, SNPs, Argentina
description Alu insertions, INDELs, and SNPs in the X chromosome can be useful not only for revealing relationships among populations but also for identification purposes. We present data of 10 Alu insertions, 5 INDELs, and 15 SNPs of X-chromosome from three Argentinian north-east cities in order to gain insight into the genetic diversity of the X chromosome within this region of the country. Data from 198 unrelated individuals belonging to Posadas, Corrientes, and Eldorado cities were genotyped for Ya5DP62, Yb8DP49, Ya5DP3, Ya5NBC37, Ya5DP77, Ya5NBC491, Ya5DP4, Ya5DP13, Yb8NBC634, and Yb8NBC102 Alu insertions, for MID193, MID1705, MID3754, MID3756 and MID1540 Indels and for rs6639398, rs5986751, rs5964206, rs9781645, rs2209420, rs1299087, rs318173, rs933315, rs1991961, rs4825889, rs1781116, rs1937193, rs1781104, rs149910, and rs652 SNPs. No deviations fromHardy-Weinberg equilibrium were observed for Posadas and Corrientes. However, Eldorado showed significant values, and it was found to have an internal substructuring with two groups of different origin, one showing higher similarity with European countries, and the other with more similarities to Posadas and Corrientes. Fst pairwise genetic distances emerged for some markers among the studied populations and also between our data and those from other countries and continents. Of particular interest, Alu insertions demonstrated the most differences, and could be of use in ancestry studies for these populations, while INDELs and SNPs variation were informative for differentiation within the country.
format Articulo
Articulo
author Di Santo Meztler, Gabriela Paula
Palacio, Santiago del
Esteban, María E.
Armoa, Isaías
Argüelles, Carina Francisca
Catanesi, Cecilia Inés
author_facet Di Santo Meztler, Gabriela Paula
Palacio, Santiago del
Esteban, María E.
Armoa, Isaías
Argüelles, Carina Francisca
Catanesi, Cecilia Inés
author_sort Di Santo Meztler, Gabriela Paula
title Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
title_short Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
title_full Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
title_fullStr Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
title_full_unstemmed Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
title_sort genetic differentiation of north-east argentina populations based on 30 binary x chromosome markers
publishDate 2018
url http://sedici.unlp.edu.ar/handle/10915/67519
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