Restauration of age related motor impairment: role of IGF-1 based gene therapy and microglial activation

In the current study we implemented ICV IGF-1 gene therapy in very old rats (28 months) and assessed the motor performance pre and 17-days after surgery. Glial immunoreactivity in striatum was evaluated by Iba1 and GFAP markers.

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Detalles Bibliográficos
Autores principales:	Falomir Lockhart, Eugenia, Millan, J., Anesetti Nelli, S., Hereñú, Claudia Beatriz, Bellini, María José
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2015
Materias:	Ciencias Médicas Microglía
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/59228 http://revista.med.unlp.edu.ar/archivos/201512/Restaurationof_age_related_motor_impairment.pdf http://revista.med.unlp.edu.ar/archivos/201512/posters/p_Restauration_of_age_related_motor_impairment_role_of_igf-1_based_gene_therapy_and_microglial_activation.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-59228
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Médicas Microglía
spellingShingle	Ciencias Médicas Microglía Falomir Lockhart, Eugenia Millan, J. Anesetti Nelli, S. Hereñú, Claudia Beatriz Bellini, María José Restauration of age related motor impairment: role of IGF-1 based gene therapy and microglial activation
topic_facet	Ciencias Médicas Microglía
description	In the current study we implemented ICV IGF-1 gene therapy in very old rats (28 months) and assessed the motor performance pre and 17-days after surgery. Glial immunoreactivity in striatum was evaluated by Iba1 and GFAP markers.
format	Articulo Comunicacion
author	Falomir Lockhart, Eugenia Millan, J. Anesetti Nelli, S. Hereñú, Claudia Beatriz Bellini, María José
author_facet	Falomir Lockhart, Eugenia Millan, J. Anesetti Nelli, S. Hereñú, Claudia Beatriz Bellini, María José
author_sort	Falomir Lockhart, Eugenia
title	Restauration of age related motor impairment: role of IGF-1 based gene therapy and microglial activation
title_short	Restauration of age related motor impairment: role of IGF-1 based gene therapy and microglial activation
title_full	Restauration of age related motor impairment: role of IGF-1 based gene therapy and microglial activation
title_fullStr	Restauration of age related motor impairment: role of IGF-1 based gene therapy and microglial activation
title_full_unstemmed	Restauration of age related motor impairment: role of IGF-1 based gene therapy and microglial activation
title_sort	restauration of age related motor impairment: role of igf-1 based gene therapy and microglial activation
publishDate	2015
url	http://sedici.unlp.edu.ar/handle/10915/59228 http://revista.med.unlp.edu.ar/archivos/201512/Restaurationof_age_related_motor_impairment.pdf http://revista.med.unlp.edu.ar/archivos/201512/posters/p_Restauration_of_age_related_motor_impairment_role_of_igf-1_based_gene_therapy_and_microglial_activation.pdf
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bdutipo_str	Repositorios
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Restauration of age related motor impairment: role of IGF-1 based gene therapy and microglial activation

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