Comparison of different methods for the calculation of the microvascular flow index

The microvascular flow index (MFI) is commonly used to semiquantitatively characterize the velocity of microcirculatory perfusion as absent (0), intermittent (1), sluggish (2), or normal (3). There are three approaches to compute MFI: (1) the average of the predominant flow in each of the four quadr...

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Autores principales: Pozo, Mario Omar, Kanoore Edul, Vanina Siham, Ince, Can, Dubin, Arnaldo
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Ciencias Médicas
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/38176
http://www.hindawi.com/journals/ccrp/2012/102483/
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SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-38176
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
spellingShingle Ciencias Médicas
Pozo, Mario Omar
Kanoore Edul, Vanina Siham
Ince, Can
Dubin, Arnaldo
Comparison of different methods for the calculation of the microvascular flow index
topic_facet Ciencias Médicas
description The microvascular flow index (MFI) is commonly used to semiquantitatively characterize the velocity of microcirculatory perfusion as absent (0), intermittent (1), sluggish (2), or normal (3). There are three approaches to compute MFI: (1) the average of the predominant flow in each of the four quadrants (MFI <SUB>by quadrants</SUB>), (2) the direct assessment during the bedside video acquisition (MFI <SUB>point of care</SUB>), and (3) the mean value of the MFIs determined in each individual vessel (MFI <SUB>vessel by vessel</SUB>). We hypothesized that the agreement between the MFIs is poor and that the MFI <SUB>vessel by vessel</SUB> better reflects the microvascular perfusion. For this purpose, we analyzed 100 videos from septic patients. In 25 of them, red blood cell (RBC) velocity was also measured. There were wide 95% limits of agreement between MFI <SUB>by quadrants</SUB> and MFI <SUB>point of care</SUB> (1.46), between MFI <SUB>by quadrants</SUB> and MFI <SUB>vessel by vessel</SUB> (2.85), and between MFI <SUB>by point of care</SUB> and MFI <SUB>vessel by vessel</SUB> (2.56). The MFIs significantly correlated with the RBC velocity and with the fraction of perfused small vessels, but MFI <SUB>vessel by vessel</SUB> showed the best R 2. Although the different methods for the calculation of MFI reflect microvascular perfusion, they are not interchangeable and MFI <SUB>vessel by vessel</SUB> might be better.
format Articulo
Articulo
author Pozo, Mario Omar
Kanoore Edul, Vanina Siham
Ince, Can
Dubin, Arnaldo
author_facet Pozo, Mario Omar
Kanoore Edul, Vanina Siham
Ince, Can
Dubin, Arnaldo
author_sort Pozo, Mario Omar
title Comparison of different methods for the calculation of the microvascular flow index
title_short Comparison of different methods for the calculation of the microvascular flow index
title_full Comparison of different methods for the calculation of the microvascular flow index
title_fullStr Comparison of different methods for the calculation of the microvascular flow index
title_full_unstemmed Comparison of different methods for the calculation of the microvascular flow index
title_sort comparison of different methods for the calculation of the microvascular flow index
publishDate 2012
url http://sedici.unlp.edu.ar/handle/10915/38176
http://www.hindawi.com/journals/ccrp/2012/102483/
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AT dubinarnaldo comparisonofdifferentmethodsforthecalculationofthemicrovascularflowindex
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