Experimental intoxication by the leaves of <i>Melia azedarach</i> (Meliaceae) in cattle

Green leaves of <i>Melia azedarach</i> were administered at single doses ranging from 5 to 30 g/ kg bw to 11 calves. Clinical signs were depression, ruminal stasis, dry feces with blood, ataxia, muscle tremors, sternal recumbency, hypothermia and abdominal pain. Serum AST and CPK were in...

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Autores principales:	Méndez González, María del Carmen, Aragão, Marcos, Elías, Fabiana, Riet Correa, Franklin, Gimeno, Eduardo Juan
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2002
Materias:	Ciencias Veterinarias cattle creatine kinase hematochezia Melia azedarach Meliaceae hyaline degeneration hypothermia plant poisoning poisonous plants intestine injury intoxication macrophage phytotoxicity
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/35792 http://www.scielo.br/pdf/pvb/v22n1/8867.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Veterinarias cattle creatine kinase hematochezia Melia azedarach Meliaceae hyaline degeneration hypothermia plant poisoning poisonous plants intestine injury intoxication macrophage phytotoxicity
spellingShingle	Ciencias Veterinarias cattle creatine kinase hematochezia Melia azedarach Meliaceae hyaline degeneration hypothermia plant poisoning poisonous plants intestine injury intoxication macrophage phytotoxicity Méndez González, María del Carmen Aragão, Marcos Elías, Fabiana Riet Correa, Franklin Gimeno, Eduardo Juan Experimental intoxication by the leaves of <i>Melia azedarach</i> (Meliaceae) in cattle
topic_facet	Ciencias Veterinarias cattle creatine kinase hematochezia Melia azedarach Meliaceae hyaline degeneration hypothermia plant poisoning poisonous plants intestine injury intoxication macrophage phytotoxicity
description	Green leaves of <i>Melia azedarach</i> were administered at single doses ranging from 5 to 30 g/ kg bw to 11 calves. Clinical signs were depression, ruminal stasis, dry feces with blood, ataxia, muscle tremors, sternal recumbency, hypothermia and abdominal pain. Serum AST and CPK were increased. Signs appeared from 8 to 24 hours after dosing, and the clinical course lasted from 2 to 72 hours. Three calves dosed with 30g/kg bw died. The macroscopic findings included intestinal congestion, yellow discoloration of the liver, brain congestion and dry feces with blood in the rectum. The liver showed swollen and vacuolated hepatocytes. Necrotic hepatocytes were scattered throughout the parenchyma or concentrated in the periacinar zone. Degenerative and necrotic changes were observed in the epithelium of the forestomachs. There was also necrosis of the lymphoid tissue. Skeletal muscles showed hyaline degeneration and fiber necrosis. The necrotic fragments contained floccular or granular debris with infiltration by macrophages and satellite cells.
format	Articulo Articulo
author	Méndez González, María del Carmen Aragão, Marcos Elías, Fabiana Riet Correa, Franklin Gimeno, Eduardo Juan
author_facet	Méndez González, María del Carmen Aragão, Marcos Elías, Fabiana Riet Correa, Franklin Gimeno, Eduardo Juan
author_sort	Méndez González, María del Carmen
title	Experimental intoxication by the leaves of <i>Melia azedarach</i> (Meliaceae) in cattle
title_short	Experimental intoxication by the leaves of <i>Melia azedarach</i> (Meliaceae) in cattle
title_full	Experimental intoxication by the leaves of <i>Melia azedarach</i> (Meliaceae) in cattle
title_fullStr	Experimental intoxication by the leaves of <i>Melia azedarach</i> (Meliaceae) in cattle
title_full_unstemmed	Experimental intoxication by the leaves of <i>Melia azedarach</i> (Meliaceae) in cattle
title_sort	experimental intoxication by the leaves of <i>melia azedarach</i> (meliaceae) in cattle
publishDate	2002
url	http://sedici.unlp.edu.ar/handle/10915/35792 http://www.scielo.br/pdf/pvb/v22n1/8867.pdf
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bdutipo_str	Repositorios
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Experimental intoxication by the leaves of <i>Melia azedarach</i> (Meliaceae) in cattle

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