Cooperative binding of transcription factors promotes bimodal gene expression response

In the present work we extend and analyze the scope of our recently proposed stochastic model for transcriptional regulation, which considers an arbitrarily complex cis-regulatory system using only elementary reactions. Previously, we determined the role of cooperativity on the intrinsic fluctuation...

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Detalles Bibliográficos
Autores principales: Gutiérrez, Pablo S., Monteoliva, Diana, Diambra, Luis Aníbal
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Ciencias Exactas
Física
Factores de Transcripción
Proteínas de Unión al ADN
ARN Mensajero
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/29762
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0044812
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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