In vitro and in vivo susceptibility of the honey bee bacterial pathogen <i>Paenibacillus larvae subsp. larvae</i> to the antibiotic tylosin

The minimal inhibitory concentrations (MICs) of tylosin were determined to 67 strains of Paenibacillus larvae subsp. larvae, the causal agent of American Foulbrood (AFB) disease, from different geographical origins. MIC values obtained ranged from 0.0078 to 0.5 microg/ml. These very low values imply...

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Autores principales: Alippi, Adriana Mónica, Albo, Graciela Noemí, Reynaldi, Francisco José, De Giusti, Marisa Raquel
Formato: Articulo
Lenguaje:Inglés
Publicado: 2005
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/27127
http://www.sciencedirect.com/science/article/pii/S0378113505001112
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id I19-R120-10915-27127
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ingeniería
Ciencias Agrarias
honeybees
Interacciones Huésped-Patógeno
Abejas
tylosin
foulbrood
spellingShingle Ingeniería
Ciencias Agrarias
honeybees
Interacciones Huésped-Patógeno
Abejas
tylosin
foulbrood
Alippi, Adriana Mónica
Albo, Graciela Noemí
Reynaldi, Francisco José
De Giusti, Marisa Raquel
In vitro and in vivo susceptibility of the honey bee bacterial pathogen <i>Paenibacillus larvae subsp. larvae</i> to the antibiotic tylosin
topic_facet Ingeniería
Ciencias Agrarias
honeybees
Interacciones Huésped-Patógeno
Abejas
tylosin
foulbrood
description The minimal inhibitory concentrations (MICs) of tylosin were determined to 67 strains of Paenibacillus larvae subsp. larvae, the causal agent of American Foulbrood (AFB) disease, from different geographical origins. MIC values obtained ranged from 0.0078 to 0.5 microg/ml. These very low values imply that no resistance to tylosin was found in any isolate of the Foulbrood pathogen. The measurement of diseased larvae with AFB-clinical symptoms in three different field studies demonstrated that tylosin treatment could be effective in vivo. No negative effects in colonies were noted at any dosage rates or forms of application. These studies demonstrate that tylosin, as tartrate, can be used to treat AFB in honeybee colonies.
format Articulo
Articulo
author Alippi, Adriana Mónica
Albo, Graciela Noemí
Reynaldi, Francisco José
De Giusti, Marisa Raquel
author_facet Alippi, Adriana Mónica
Albo, Graciela Noemí
Reynaldi, Francisco José
De Giusti, Marisa Raquel
author_sort Alippi, Adriana Mónica
title In vitro and in vivo susceptibility of the honey bee bacterial pathogen <i>Paenibacillus larvae subsp. larvae</i> to the antibiotic tylosin
title_short In vitro and in vivo susceptibility of the honey bee bacterial pathogen <i>Paenibacillus larvae subsp. larvae</i> to the antibiotic tylosin
title_full In vitro and in vivo susceptibility of the honey bee bacterial pathogen <i>Paenibacillus larvae subsp. larvae</i> to the antibiotic tylosin
title_fullStr In vitro and in vivo susceptibility of the honey bee bacterial pathogen <i>Paenibacillus larvae subsp. larvae</i> to the antibiotic tylosin
title_full_unstemmed In vitro and in vivo susceptibility of the honey bee bacterial pathogen <i>Paenibacillus larvae subsp. larvae</i> to the antibiotic tylosin
title_sort in vitro and in vivo susceptibility of the honey bee bacterial pathogen <i>paenibacillus larvae subsp. larvae</i> to the antibiotic tylosin
publishDate 2005
url http://sedici.unlp.edu.ar/handle/10915/27127
http://www.sciencedirect.com/science/article/pii/S0378113505001112
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