Tailoring binary and tertiary solid dispersion compositions of nelfinavir using spray drying

In order to reduce the recrystallinity of poorly insoluble drug nelfinavir, PEG 6000 blends were prepared by spray drying with HPMC. The maximal reduction of recrystallinity in PEG 6000 was obtained by co-spray drying with HPMC as revealed by in vitro dissolution studies. The resulting ternary so...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Barik, B. B., Dewani, Sunil P.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Differential scanning calorimetry
HPMC
Nelfinavir
PEG 6000
Solid dispersion
Spray drying
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/25734
http://www.latamjpharm.org/resumenes/31/7/LAJOP_31_7_1_2.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

Ejemplares similares

Ejemplares similares