Pk/pd of morphine for postoperative analgesia after coronary artery bypass grafting : Intrathecal morphine significantly reduces drug consumption

The aim of the present study was to evaluate intrathecal morphine outcome on postoperative pain and apply pharmacokinetic/pharmacodynamic model to justify morphine consumption, plasma concentration and pain intensity during coronary artery bypass grafting surgery. Thirty six patients were prospectiv...

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Detalles Bibliográficos
Autores principales: Santos, Veronica C.J., Sanches Giraud, Cristina, Lanchote, Vera L., Santos, Luciana M., Carmona, María J. C., Santos, Silvia R. C. J.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Analgesia
Intrathecal morphine
Pharmacokinetic/pharmacodynamic modeling
Postoperative patient-controlled analgesia device
Morfina
Farmacocinética
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/20219
http://www.latamjpharm.org/resumenes/31/5/LAJOP_31_5_1_7.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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