Simultaneous Determination of Three Bioactive Compounds in Traditional Chinese Medicine Patent Prescription Zuojin Pill by HPLC
A high-performance liquid chromatography (HPLC) method coupled with ultraviolet (UV) detection has been developed and validated for simultaneous quantification of berberine hydrochloride, evodiamine and rutaecarpine in Zuojin Pill. Chromatographic separation were achieved on a ODS-C18 column (250×4....
Guardado en:
| Autores principales: | , , , , , , |
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| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/18253 http://www.latamjpharm.org/resumenes/31/3/LAJOP_31_3_1_6.pdf |
| Aporte de: |
| id |
I19-R120-10915-18253 |
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| record_format |
dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Farmacia Farmacología berberine hydrochloride; evodiamine; HPLC; rutaecarpine; Zuojin pill Medicina Tradicional |
| spellingShingle |
Farmacia Farmacología berberine hydrochloride; evodiamine; HPLC; rutaecarpine; Zuojin pill Medicina Tradicional Cai, Jinzhang Huang, Zhenzhen Chen, Chan Xu, Ren-ai Lin, Chongliang Lin, Guanyang Wang, Xianqin Simultaneous Determination of Three Bioactive Compounds in Traditional Chinese Medicine Patent Prescription Zuojin Pill by HPLC |
| topic_facet |
Farmacia Farmacología berberine hydrochloride; evodiamine; HPLC; rutaecarpine; Zuojin pill Medicina Tradicional |
| description |
A high-performance liquid chromatography (HPLC) method coupled with ultraviolet (UV) detection has been developed and validated for simultaneous quantification of berberine hydrochloride, evodiamine and rutaecarpine in Zuojin Pill. Chromatographic separation were achieved on a ODS-C18 column (250×4.6 mm i.d., 5.0 μm particle) through a 25 min gradient delivery of a mixture of A (acetonitrile) and B (0.3 % phosphoric acid-0.3 % triethylamine) at a flow rate of 0.8 mL/min at 40 °C. All of the analytes showed good linearity (r > 0.999). The method was validated for repeatability, precision, stability, accuracy and selectivity. The validated method was applied to quality control of Zuojin Pill from different manufacture. |
| format |
Articulo Articulo |
| author |
Cai, Jinzhang Huang, Zhenzhen Chen, Chan Xu, Ren-ai Lin, Chongliang Lin, Guanyang Wang, Xianqin |
| author_facet |
Cai, Jinzhang Huang, Zhenzhen Chen, Chan Xu, Ren-ai Lin, Chongliang Lin, Guanyang Wang, Xianqin |
| author_sort |
Cai, Jinzhang |
| title |
Simultaneous Determination of Three Bioactive Compounds in Traditional Chinese Medicine Patent Prescription Zuojin Pill by HPLC |
| title_short |
Simultaneous Determination of Three Bioactive Compounds in Traditional Chinese Medicine Patent Prescription Zuojin Pill by HPLC |
| title_full |
Simultaneous Determination of Three Bioactive Compounds in Traditional Chinese Medicine Patent Prescription Zuojin Pill by HPLC |
| title_fullStr |
Simultaneous Determination of Three Bioactive Compounds in Traditional Chinese Medicine Patent Prescription Zuojin Pill by HPLC |
| title_full_unstemmed |
Simultaneous Determination of Three Bioactive Compounds in Traditional Chinese Medicine Patent Prescription Zuojin Pill by HPLC |
| title_sort |
simultaneous determination of three bioactive compounds in traditional chinese medicine patent prescription zuojin pill by hplc |
| publishDate |
2012 |
| url |
http://sedici.unlp.edu.ar/handle/10915/18253 http://www.latamjpharm.org/resumenes/31/3/LAJOP_31_3_1_6.pdf |
| work_keys_str_mv |
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| bdutipo_str |
Repositorios |
| _version_ |
1764820463988506626 |