Mathematical Modeling of Drug Release of Novel Extended-Release Formulations of Tizanidine Hydrochloride

Six extended-release formulations of tizanidine hydrochloride were prepared by direct compression technique using hydroxypropylmethylcellulose (HPMC) and ethylcellulose (EC). The drug release from these tablets was evaluated by analyzing the samples at 227 nm. Both model dependent and independent ma...

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Detalles Bibliográficos
Autores principales: Naeem, Muhammad, Akhter, Khalid P., Ahmad, Ajaz, Aamir, Muhammad N., Aslam, Zartasha
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Farmacología
ethylcellulose; extended-release tablets; factorial design; hydroxypropyl methylcellulose; kinetic models; mathematical modeling; tizanidine hydrochloride
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/18246
http://www.latamjpharm.org/resumenes/31/3/LAJOP_31_3_1_4.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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