In vitro Efficacy of Photoprotection in Sunscreens: a Comparison Between Methods

Sunscreens are known to play an important role on the prevention of skin cancer, as they act by blocking the carcinogenic solar radiations. The currently methods for determining the sun protection efficacy of these products are all based on in vivo tests. In this light, the aim of the present study...

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Autores principales: Polonini, Hudson C., Gomes, Thiago B. B., Gonçalves, Karla M., Brandão, Marcos A. F., Raposo, Nádia N. B.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/18243
http://www.latamjpharm.org/resumenes/31/3/LAJOP_31_3_1_1.pdf
Aporte de:
id I19-R120-10915-18243
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Broad spectrum sunscreen; diffuse transmittance; sun protection factor
Agentes Protectores de Rayos Solares
Aplicaciones Terapéuticas
Agentes Dermatológicos
spellingShingle Farmacia
Broad spectrum sunscreen; diffuse transmittance; sun protection factor
Agentes Protectores de Rayos Solares
Aplicaciones Terapéuticas
Agentes Dermatológicos
Polonini, Hudson C.
Gomes, Thiago B. B.
Gonçalves, Karla M.
Brandão, Marcos A. F.
Raposo, Nádia N. B.
In vitro Efficacy of Photoprotection in Sunscreens: a Comparison Between Methods
topic_facet Farmacia
Broad spectrum sunscreen; diffuse transmittance; sun protection factor
Agentes Protectores de Rayos Solares
Aplicaciones Terapéuticas
Agentes Dermatológicos
description Sunscreens are known to play an important role on the prevention of skin cancer, as they act by blocking the carcinogenic solar radiations. The currently methods for determining the sun protection efficacy of these products are all based on in vivo tests. In this light, the aim of the present study was to compare the performance of two spectrophotometric in vitro methods, in order to determine which one generates more trustworthy Sun Protection Factors (SPF) values: the classical UV spectrophotometry or the diffuse transmittance reflectance spectrophotometry. For that, twenty-five SPF 30 commercial sunscreen samples were used. The methods generated different results, being the diffuse transmittance spectrophotometry more appropriate and reliable for determining the SPF of these products. Moreover, it provides as additional advantage the possibility of quantifying the protection against UVA radiation through the UVA/UVB Ratio and the Critical Wavelength.
format Articulo
Articulo
author Polonini, Hudson C.
Gomes, Thiago B. B.
Gonçalves, Karla M.
Brandão, Marcos A. F.
Raposo, Nádia N. B.
author_facet Polonini, Hudson C.
Gomes, Thiago B. B.
Gonçalves, Karla M.
Brandão, Marcos A. F.
Raposo, Nádia N. B.
author_sort Polonini, Hudson C.
title In vitro Efficacy of Photoprotection in Sunscreens: a Comparison Between Methods
title_short In vitro Efficacy of Photoprotection in Sunscreens: a Comparison Between Methods
title_full In vitro Efficacy of Photoprotection in Sunscreens: a Comparison Between Methods
title_fullStr In vitro Efficacy of Photoprotection in Sunscreens: a Comparison Between Methods
title_full_unstemmed In vitro Efficacy of Photoprotection in Sunscreens: a Comparison Between Methods
title_sort in vitro efficacy of photoprotection in sunscreens: a comparison between methods
publishDate 2012
url http://sedici.unlp.edu.ar/handle/10915/18243
http://www.latamjpharm.org/resumenes/31/3/LAJOP_31_3_1_1.pdf
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