Formulation development and optimization of cefuroxime axetil tablets by direct compression method and its stability studies

Cefuroxime axetil (CA) immediate release (IR) tablets were developed and optimized by direct compression method. Ten formulations were designed and optimized using central composite design with two main variables, microcrystalline cellulose PH 102 and croscarmellose. Pharmaceutical evaluation of the...

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Detalles Bibliográficos
Autores principales: Muhammad, Iyad N., Yousuf, Rabia I., Hanif, Muhammad, Shoaib, Muhammad Harris, Jabeen, Sabahat, Ali, Tariq
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Farmacología
cefuroxime axetil; centre composite design; formulation development; formulation optimization; similarity factor f2; stability under stress conditions
Cefuroxima
Compuestos Orgánicos
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/18124
http://www.latamjpharm.org/resumenes/31/2/LAJOP_31_2_1_15.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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