Self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles

Medical device-related infections represent a major healthcare complication, resulting in potential risks for the patient. Antimicrobial materials comprise an attractive strategy against bacterial colonization and biofilm proliferation. However, in most cases these materials are only bacteriostatic...

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Autores principales: Gonçalves, Lidiane Patricia, Miñán, Alejandro Guillermo, Benitez, Guillermo Alfredo, Fernández Lorenzo de Mele, Mónica Alicia, Vela, María Elena, Schilardi, Patricia Laura, Ferreira Neto, Elias Paiva, Noveletto, Júlia Cristina, Correr, Wagner Rafael, Pereira Rodrigues-Filho, Ubirajara
Formato: Articulo
Lenguaje:Inglés
Publicado: 2018
Materias:
Ciencias Exactas
Química
antibacterial activity
Pseudomonas aeruginosa
Staphylococcus aureus
ormosil
Ag nanoparticles
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/163488
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-163488
record_format dspace
spelling I19-R120-10915-1634882024-03-06T20:11:21Z http://sedici.unlp.edu.ar/handle/10915/163488 Self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles Gonçalves, Lidiane Patricia Miñán, Alejandro Guillermo Benitez, Guillermo Alfredo Fernández Lorenzo de Mele, Mónica Alicia Vela, María Elena Schilardi, Patricia Laura Ferreira Neto, Elias Paiva Noveletto, Júlia Cristina Correr, Wagner Rafael Pereira Rodrigues-Filho, Ubirajara 2018 2024-03-06T13:50:43Z en Ciencias Exactas Química antibacterial activity Pseudomonas aeruginosa Staphylococcus aureus ormosil Ag nanoparticles Medical device-related infections represent a major healthcare complication, resulting in potential risks for the patient. Antimicrobial materials comprise an attractive strategy against bacterial colonization and biofilm proliferation. However, in most cases these materials are only bacteriostatic or bactericidal, and consequently they must be used in combination with other antimicrobials in order to reach the eradication condition (no viable microorganisms). In this study, a straightforward and robust antibacterial coating based on Phosphotungstate Ormosil doped with core-shell (SiO₂@TiO₂) was developed using sol-gel process, chemical tempering, and Ag nanoparticle photoassisted synthesis (POrs-CS-Ag). The coating was characterized by X-ray Fluorescence Spectroscopy (XRF), Field Emission Scanning Electron Microscopy (FE-SEM), Atomic Force Microscopy (AFM) and X-ray Photoelectron Microscopy (XPS). The silver free coating displays low antibacterial activity against "Staphylococcus aureus" and "Pseudomonas aeruginosa", in opposition to the silver loaded ones, which are able to completely eradicate these strains. Moreover, the antimicrobial activity of these substrates remains high until three reutilization cycles, which make them a promising strategy to develop self-sterilizing materials, such as POrs-CS-Ag-impregnated fabric, POrs-CS-Ag coated indwelling metals and polymers, among other materials. Facultad de Ciencias Exactas Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas Articulo Articulo http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International (CC BY 4.0) application/pdf 144-154
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Exactas
Química
antibacterial activity
Pseudomonas aeruginosa
Staphylococcus aureus
ormosil
Ag nanoparticles
spellingShingle Ciencias Exactas
Química
antibacterial activity
Pseudomonas aeruginosa
Staphylococcus aureus
ormosil
Ag nanoparticles
Gonçalves, Lidiane Patricia
Miñán, Alejandro Guillermo
Benitez, Guillermo Alfredo
Fernández Lorenzo de Mele, Mónica Alicia
Vela, María Elena
Schilardi, Patricia Laura
Ferreira Neto, Elias Paiva
Noveletto, Júlia Cristina
Correr, Wagner Rafael
Pereira Rodrigues-Filho, Ubirajara
Self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles
topic_facet Ciencias Exactas
Química
antibacterial activity
Pseudomonas aeruginosa
Staphylococcus aureus
ormosil
Ag nanoparticles
description Medical device-related infections represent a major healthcare complication, resulting in potential risks for the patient. Antimicrobial materials comprise an attractive strategy against bacterial colonization and biofilm proliferation. However, in most cases these materials are only bacteriostatic or bactericidal, and consequently they must be used in combination with other antimicrobials in order to reach the eradication condition (no viable microorganisms). In this study, a straightforward and robust antibacterial coating based on Phosphotungstate Ormosil doped with core-shell (SiO₂@TiO₂) was developed using sol-gel process, chemical tempering, and Ag nanoparticle photoassisted synthesis (POrs-CS-Ag). The coating was characterized by X-ray Fluorescence Spectroscopy (XRF), Field Emission Scanning Electron Microscopy (FE-SEM), Atomic Force Microscopy (AFM) and X-ray Photoelectron Microscopy (XPS). The silver free coating displays low antibacterial activity against "Staphylococcus aureus" and "Pseudomonas aeruginosa", in opposition to the silver loaded ones, which are able to completely eradicate these strains. Moreover, the antimicrobial activity of these substrates remains high until three reutilization cycles, which make them a promising strategy to develop self-sterilizing materials, such as POrs-CS-Ag-impregnated fabric, POrs-CS-Ag coated indwelling metals and polymers, among other materials.
format Articulo
Articulo
author Gonçalves, Lidiane Patricia
Miñán, Alejandro Guillermo
Benitez, Guillermo Alfredo
Fernández Lorenzo de Mele, Mónica Alicia
Vela, María Elena
Schilardi, Patricia Laura
Ferreira Neto, Elias Paiva
Noveletto, Júlia Cristina
Correr, Wagner Rafael
Pereira Rodrigues-Filho, Ubirajara
author_facet Gonçalves, Lidiane Patricia
Miñán, Alejandro Guillermo
Benitez, Guillermo Alfredo
Fernández Lorenzo de Mele, Mónica Alicia
Vela, María Elena
Schilardi, Patricia Laura
Ferreira Neto, Elias Paiva
Noveletto, Júlia Cristina
Correr, Wagner Rafael
Pereira Rodrigues-Filho, Ubirajara
author_sort Gonçalves, Lidiane Patricia
title Self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles
title_short Self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles
title_full Self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles
title_fullStr Self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles
title_full_unstemmed Self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles
title_sort self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles
publishDate 2018
url http://sedici.unlp.edu.ar/handle/10915/163488
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