Hantavirus in rodents of Buenos Aires Province: are seroprevalence and abundance related?

Oligoryzomys flavescens and Akodon azarae are two rodent species living in agroecosystems of the Pampean region. O. flavescens is a reservoir of the Lechiguanas genotype, associated with Hantavirus Pulmonary Syndrome, whereas Akodon azarae is a reservoir of the Pergamino genotype, which has not been...

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Autores principales: Gorosito, Irene L., Bellomo, Carla, Martínez, Paula V., Busch, María
Formato: Objeto de conferencia
Lenguaje:Inglés
Publicado: 2022
Materias:
Ciencias Naturales
viral haemorrhagic fevers
vector biology
eco-epidemiology
rodents
seroprevalence
abundance related
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/155125
https://www.youtube.com/watch?v=fY6MZMvyLQQ
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-155125
record_format dspace
spelling I19-R120-10915-1551252023-07-06T20:01:48Z http://sedici.unlp.edu.ar/handle/10915/155125 https://www.youtube.com/watch?v=fY6MZMvyLQQ Hantavirus in rodents of Buenos Aires Province: are seroprevalence and abundance related? Gorosito, Irene L. Bellomo, Carla Martínez, Paula V. Busch, María 2022-11-01 2022 2023-07-06T12:42:33Z en Ciencias Naturales viral haemorrhagic fevers vector biology eco-epidemiology rodents seroprevalence abundance related Oligoryzomys flavescens and Akodon azarae are two rodent species living in agroecosystems of the Pampean region. O. flavescens is a reservoir of the Lechiguanas genotype, associated with Hantavirus Pulmonary Syndrome, whereas Akodon azarae is a reservoir of the Pergamino genotype, which has not been associated with human cases. Our objective was to evaluate whether there is a relationship between abundance and seroprevalence in both rodent species, as this may help to identify situations of high risk of exposure to hantavirus for humans. Eleven longitudinal rodent capture-mark-recapture surveys were conducted in three railway embankments in agricultural landscapes (Exaltación de la Cruz Departament, Buenos Aires province, Argentina), from 2014 through 2016. The trapping effort was 1800 trap-nights per survey. During these surveys, demographic data and blood samples were collected. Blood samples were analyzed by means of ELISAs to determine the presence of hantavirus-specific antibodies. For each rodent species, the relationship between seroprevalence and its abundance was assessed through logit-linked binomial generalized linear models using the number of infected individuals by sampling session as the response variable (i.e., successees, with the corresponding number of tested blood samples per group as trials). Models containing the species’ MNA as a predictor and the null models were evaluated. Using a multi-model approach, averaged parameters and their relative importance were calculated using Akaike weights (AIC). The main finding in this work was that both A. azarae and O. flavescens exhibit a negative relationship between prevalence and abundance. A possible explanation for this result is that populations reach their smaller numbers when these consist mainly of overwintering adults, which had longer exposures with higher chances of becoming infected, whereas larger populations are observed soon after the reproductive season, when new recruits are unlikely to be infected yet. Thus, the effect of prevalence and abundance on the risk of human exposure could be compensatory. This suggests that there would be no particular season of increased risk; prevention and surveillance should be permanent. Para acceder a la videoconferencia completa, hacer clic en "Enlace externo". Sociedad Latinoamericana de Ecología de Vectores Objeto de conferencia Objeto de conferencia http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Naturales
viral haemorrhagic fevers
vector biology
eco-epidemiology
rodents
seroprevalence
abundance related
spellingShingle Ciencias Naturales
viral haemorrhagic fevers
vector biology
eco-epidemiology
rodents
seroprevalence
abundance related
Gorosito, Irene L.
Bellomo, Carla
Martínez, Paula V.
Busch, María
Hantavirus in rodents of Buenos Aires Province: are seroprevalence and abundance related?
topic_facet Ciencias Naturales
viral haemorrhagic fevers
vector biology
eco-epidemiology
rodents
seroprevalence
abundance related
description Oligoryzomys flavescens and Akodon azarae are two rodent species living in agroecosystems of the Pampean region. O. flavescens is a reservoir of the Lechiguanas genotype, associated with Hantavirus Pulmonary Syndrome, whereas Akodon azarae is a reservoir of the Pergamino genotype, which has not been associated with human cases. Our objective was to evaluate whether there is a relationship between abundance and seroprevalence in both rodent species, as this may help to identify situations of high risk of exposure to hantavirus for humans. Eleven longitudinal rodent capture-mark-recapture surveys were conducted in three railway embankments in agricultural landscapes (Exaltación de la Cruz Departament, Buenos Aires province, Argentina), from 2014 through 2016. The trapping effort was 1800 trap-nights per survey. During these surveys, demographic data and blood samples were collected. Blood samples were analyzed by means of ELISAs to determine the presence of hantavirus-specific antibodies. For each rodent species, the relationship between seroprevalence and its abundance was assessed through logit-linked binomial generalized linear models using the number of infected individuals by sampling session as the response variable (i.e., successees, with the corresponding number of tested blood samples per group as trials). Models containing the species’ MNA as a predictor and the null models were evaluated. Using a multi-model approach, averaged parameters and their relative importance were calculated using Akaike weights (AIC). The main finding in this work was that both A. azarae and O. flavescens exhibit a negative relationship between prevalence and abundance. A possible explanation for this result is that populations reach their smaller numbers when these consist mainly of overwintering adults, which had longer exposures with higher chances of becoming infected, whereas larger populations are observed soon after the reproductive season, when new recruits are unlikely to be infected yet. Thus, the effect of prevalence and abundance on the risk of human exposure could be compensatory. This suggests that there would be no particular season of increased risk; prevention and surveillance should be permanent.
format Objeto de conferencia
Objeto de conferencia
author Gorosito, Irene L.
Bellomo, Carla
Martínez, Paula V.
Busch, María
author_facet Gorosito, Irene L.
Bellomo, Carla
Martínez, Paula V.
Busch, María
author_sort Gorosito, Irene L.
title Hantavirus in rodents of Buenos Aires Province: are seroprevalence and abundance related?
title_short Hantavirus in rodents of Buenos Aires Province: are seroprevalence and abundance related?
title_full Hantavirus in rodents of Buenos Aires Province: are seroprevalence and abundance related?
title_fullStr Hantavirus in rodents of Buenos Aires Province: are seroprevalence and abundance related?
title_full_unstemmed Hantavirus in rodents of Buenos Aires Province: are seroprevalence and abundance related?
title_sort hantavirus in rodents of buenos aires province: are seroprevalence and abundance related?
publishDate 2022
url http://sedici.unlp.edu.ar/handle/10915/155125
https://www.youtube.com/watch?v=fY6MZMvyLQQ
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