An overview of vanadium and cell signaling in potential cancer treatments
Vanadium is an ultratrace element present in higher plants, animals, algae, and bacteria. In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to va...
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| Formato: | Articulo Revision |
| Lenguaje: | Inglés |
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2022
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| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/154413 |
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I19-R120-10915-154413 |
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I19-R120-10915-1544132023-06-16T04:06:16Z http://sedici.unlp.edu.ar/handle/10915/154413 issn:2304-6740 An overview of vanadium and cell signaling in potential cancer treatments Ferretti, Valeria Alejandra León, Ignacio Esteban 2022 2023-06-15T18:01:55Z en Biología Química Vanadium biochemistry Cell signaling Cancer Anticancer agents Vanadium is an ultratrace element present in higher plants, animals, algae, and bacteria. In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to vanadium compounds has scarcely been reported on and reviewed thus far; this information is highly critical for identifying novel targets that play a key role in the anticancer activity of these compounds. Here, we perform a review of the activity of vanadium compounds over cell signaling pathways on cancer cells and of the underlying mechanisms, thereby providing insight into the role of these proteins as potential new molecular targets of vanadium complexes. Centro de Química Inorgánica Articulo Revision http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International (CC BY 4.0) application/pdf |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Biología Química Vanadium biochemistry Cell signaling Cancer Anticancer agents |
| spellingShingle |
Biología Química Vanadium biochemistry Cell signaling Cancer Anticancer agents Ferretti, Valeria Alejandra León, Ignacio Esteban An overview of vanadium and cell signaling in potential cancer treatments |
| topic_facet |
Biología Química Vanadium biochemistry Cell signaling Cancer Anticancer agents |
| description |
Vanadium is an ultratrace element present in higher plants, animals, algae, and bacteria.
In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to vanadium compounds has scarcely been reported on and reviewed thus far; this information is highly critical for identifying novel targets that play a key role in the anticancer activity of these compounds. Here, we perform a review of the activity of vanadium compounds over cell signaling pathways on cancer cells and of the underlying mechanisms, thereby providing insight into the role of these proteins as potential new molecular targets of vanadium complexes. |
| format |
Articulo Revision |
| author |
Ferretti, Valeria Alejandra León, Ignacio Esteban |
| author_facet |
Ferretti, Valeria Alejandra León, Ignacio Esteban |
| author_sort |
Ferretti, Valeria Alejandra |
| title |
An overview of vanadium and cell signaling in potential cancer treatments |
| title_short |
An overview of vanadium and cell signaling in potential cancer treatments |
| title_full |
An overview of vanadium and cell signaling in potential cancer treatments |
| title_fullStr |
An overview of vanadium and cell signaling in potential cancer treatments |
| title_full_unstemmed |
An overview of vanadium and cell signaling in potential cancer treatments |
| title_sort |
overview of vanadium and cell signaling in potential cancer treatments |
| publishDate |
2022 |
| url |
http://sedici.unlp.edu.ar/handle/10915/154413 |
| work_keys_str_mv |
AT ferrettivaleriaalejandra anoverviewofvanadiumandcellsignalinginpotentialcancertreatments AT leonignacioesteban anoverviewofvanadiumandcellsignalinginpotentialcancertreatments AT ferrettivaleriaalejandra overviewofvanadiumandcellsignalinginpotentialcancertreatments AT leonignacioesteban overviewofvanadiumandcellsignalinginpotentialcancertreatments |
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1768902333212655616 |