Suppression of estrus in cats with melatonin implants

The objective of this study was to assess the efficacy of a subcutaneous melatonin implant to suppress estrus in queens (felis catus). The hypothesis was that this implant would temporarily and reversibly suppress estrus in queens without producing any clinically detectable side effects. Fourteen ad...

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Detalles Bibliográficos
Autores principales: Giménez, F., Stornelli, María Cecilia, Tittarelli, Claudia Marcela, Savignone, César Augusto, Dorna, I. V., Sota, Rodolfo Luzbel de la, Stornelli, María Alejandra
Formato: Articulo
Lenguaje:Inglés
Publicado: 2009
Materias:
Ciencias Veterinarias
Contraception
Domestic cat
Melatonin implants
Reversible
Slow-release implants
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/149287
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-149287
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Contraception
Domestic cat
Melatonin implants
Reversible
Slow-release implants
spellingShingle Ciencias Veterinarias
Contraception
Domestic cat
Melatonin implants
Reversible
Slow-release implants
Giménez, F.
Stornelli, María Cecilia
Tittarelli, Claudia Marcela
Savignone, César Augusto
Dorna, I. V.
Sota, Rodolfo Luzbel de la
Stornelli, María Alejandra
Suppression of estrus in cats with melatonin implants
topic_facet Ciencias Veterinarias
Contraception
Domestic cat
Melatonin implants
Reversible
Slow-release implants
description The objective of this study was to assess the efficacy of a subcutaneous melatonin implant to suppress estrus in queens (felis catus). The hypothesis was that this implant would temporarily and reversibly suppress estrus in queens without producing any clinically detectable side effects. Fourteen adult queens were maintained in cages under artificial illumination (14 h light:10 h dark) for 45 d and then randomly assigned to one of two treatments. At interestrus, queens received a single subcutaneous melatonin implant (18 mg; Melovine [CEVA Sante Animal, Libourne, France]; MEL: n = 9), or a single subcutaneous placebo implant without melatonin (0 mg; PLA; n = 5). At the next estrus, all queens received a second MEL (n = 9) or PLA (n = 5) implant. Blood samples were taken when queens displayed estrous signs and during interestrus to measure estradiol (E2) and progesterone (P4), respectively, by radioimmunoassay. There were no significant differences in duration of the interestrus interval in PLA cats, regardless of whether the implants were placed during interestrus or estrus (6.0 ± 9.7 d vs. 6.0 ± 9.7 d, respectively; least square means [LSM] ± SEM). However, when MEL implants were placed during interestrus, the duration of interestrus was approximately twice as long as that occurring when MEL implants were placed during estrus (113.3 ± 6.1 d vs. 61.1 ± 6.8 d, respectively; P < 0.01). Serum E2 and P4 concentrations were similar in queens with PLA and MEL implants and in queens that received implants in estrus and interestrus. In conclusion, a subcutaneous MEL implant effectively and reversibly suppressed estrus in queens for approximately 2 to 4 mo with no clinically detectable side effects.
format Articulo
Articulo
author Giménez, F.
Stornelli, María Cecilia
Tittarelli, Claudia Marcela
Savignone, César Augusto
Dorna, I. V.
Sota, Rodolfo Luzbel de la
Stornelli, María Alejandra
author_facet Giménez, F.
Stornelli, María Cecilia
Tittarelli, Claudia Marcela
Savignone, César Augusto
Dorna, I. V.
Sota, Rodolfo Luzbel de la
Stornelli, María Alejandra
author_sort Giménez, F.
title Suppression of estrus in cats with melatonin implants
title_short Suppression of estrus in cats with melatonin implants
title_full Suppression of estrus in cats with melatonin implants
title_fullStr Suppression of estrus in cats with melatonin implants
title_full_unstemmed Suppression of estrus in cats with melatonin implants
title_sort suppression of estrus in cats with melatonin implants
publishDate 2009
url http://sedici.unlp.edu.ar/handle/10915/149287
work_keys_str_mv AT gimenezf suppressionofestrusincatswithmelatoninimplants
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