The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes

We overview the critical steps leading to the demonstration that each ~28 kD protein monomer of the water channel (or pore)¹ pierce the lipid bilayer part of the cell membrane allowing the passage of ~ 10¹³ water molecules per second. The biophysical approach gives a functional and physical image of...

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Autores principales: Gutiérrez, Antonio M., Echevarría, Miriam, Whittembury, Guillermo
Formato: Articulo Revision
Lenguaje:Inglés
Publicado: 2006
Materias:
Ciencias Médicas
Fisiología
Aquaporin
Water channels
Cell membrane
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/146979
https://pmr.safisiol.org.ar/wp-content/uploads/2022/09/vol1_n10_may.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-146979
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
Fisiología
Aquaporin
Water channels
Cell membrane
spellingShingle Ciencias Médicas
Fisiología
Aquaporin
Water channels
Cell membrane
Gutiérrez, Antonio M.
Echevarría, Miriam
Whittembury, Guillermo
The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes
topic_facet Ciencias Médicas
Fisiología
Aquaporin
Water channels
Cell membrane
description We overview the critical steps leading to the demonstration that each ~28 kD protein monomer of the water channel (or pore)¹ pierce the lipid bilayer part of the cell membrane allowing the passage of ~ 10¹³ water molecules per second. The biophysical approach gives a functional and physical image of the water pore close to what has recently been obtained from the amino acid sequence, crystallography and other advances from the cloning era of trans-membrane water transport. Paracellular “wide” water channels of some leaky epithelia are not covered here [cf. Whittembury and Reuss, 1992; Whittembury and Hill, 2000].
format Articulo
Revision
author Gutiérrez, Antonio M.
Echevarría, Miriam
Whittembury, Guillermo
author_facet Gutiérrez, Antonio M.
Echevarría, Miriam
Whittembury, Guillermo
author_sort Gutiérrez, Antonio M.
title The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes
title_short The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes
title_full The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes
title_fullStr The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes
title_full_unstemmed The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes
title_sort old water channels are aquaporin proteins through which single files of water molecules cross cell membranes
publishDate 2006
url http://sedici.unlp.edu.ar/handle/10915/146979
https://pmr.safisiol.org.ar/wp-content/uploads/2022/09/vol1_n10_may.pdf
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