Effects of equid herpesvirus 1 (EHV-1) AR8 and HH1 strains on BALB-c mice

Here, we used a murine model to describe and compare the pathogenic potential of the Argentinean equid herpesvirus 1 (EHV-1) AR8 strain with the Japanese HH1 reference strain. In AR8-inoculated animals, clinical signs began earlier, but the viremic phase was shorter. Virus isolation and DNA detectio...

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Autores principales: Zanuzzi, Carolina Natalia, Scrochi, Mariela Rita, Fuentealba, Nadia Analía, Nishida, Fabián, Portiansky, Enrique Leo, Muglia, Cecilia Isabel, Gimeno, Eduardo Juan, Barbeito, Claudio Gustavo, Galosi, Cecilia Mónica
Formato: Articulo
Lenguaje:Inglés
Publicado: 2014
Materias:
Veterinaria
Safety Index
Average Weight Gain
RK13 Cell
Equid Herpesvirus
Muench Method
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/146511
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-146511
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Veterinaria
Safety Index
Average Weight Gain
RK13 Cell
Equid Herpesvirus
Muench Method
spellingShingle Veterinaria
Safety Index
Average Weight Gain
RK13 Cell
Equid Herpesvirus
Muench Method
Zanuzzi, Carolina Natalia
Scrochi, Mariela Rita
Fuentealba, Nadia Analía
Nishida, Fabián
Portiansky, Enrique Leo
Muglia, Cecilia Isabel
Gimeno, Eduardo Juan
Barbeito, Claudio Gustavo
Galosi, Cecilia Mónica
Effects of equid herpesvirus 1 (EHV-1) AR8 and HH1 strains on BALB-c mice
topic_facet Veterinaria
Safety Index
Average Weight Gain
RK13 Cell
Equid Herpesvirus
Muench Method
description Here, we used a murine model to describe and compare the pathogenic potential of the Argentinean equid herpesvirus 1 (EHV-1) AR8 strain with the Japanese HH1 reference strain. In AR8-inoculated animals, clinical signs began earlier, but the viremic phase was shorter. Virus isolation and DNA detection in the lungs, liver and spleen were positive for both strains at different times postinfection (pi). Infection foci produced by both strains were immunohistochemically detected in lungs from day 1 to day 4 pi. We conclude that whichever EHV-1 strain is selected to experimentally reproduce the disease, it needs appropriate standardization in order to provide valid conclusions.
format Articulo
Articulo
author Zanuzzi, Carolina Natalia
Scrochi, Mariela Rita
Fuentealba, Nadia Analía
Nishida, Fabián
Portiansky, Enrique Leo
Muglia, Cecilia Isabel
Gimeno, Eduardo Juan
Barbeito, Claudio Gustavo
Galosi, Cecilia Mónica
author_facet Zanuzzi, Carolina Natalia
Scrochi, Mariela Rita
Fuentealba, Nadia Analía
Nishida, Fabián
Portiansky, Enrique Leo
Muglia, Cecilia Isabel
Gimeno, Eduardo Juan
Barbeito, Claudio Gustavo
Galosi, Cecilia Mónica
author_sort Zanuzzi, Carolina Natalia
title Effects of equid herpesvirus 1 (EHV-1) AR8 and HH1 strains on BALB-c mice
title_short Effects of equid herpesvirus 1 (EHV-1) AR8 and HH1 strains on BALB-c mice
title_full Effects of equid herpesvirus 1 (EHV-1) AR8 and HH1 strains on BALB-c mice
title_fullStr Effects of equid herpesvirus 1 (EHV-1) AR8 and HH1 strains on BALB-c mice
title_full_unstemmed Effects of equid herpesvirus 1 (EHV-1) AR8 and HH1 strains on BALB-c mice
title_sort effects of equid herpesvirus 1 (ehv-1) ar8 and hh1 strains on balb-c mice
publishDate 2014
url http://sedici.unlp.edu.ar/handle/10915/146511
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