Oxidative desaturation of α-linolenic, linoleic, and stearic acids by human liver microsomes
The desaturation of stearic, linoleic, and α-linolenic acids by human liver microsomes were studied. The microsomes were isolated from liver biopsies obtained during operations. It was shown that human liver microsomes are able to desaturate 1-¹⁴C-α-linolenic acid to octadeca-6,9,12,15-tetraenoic ac...
Guardado en:
| Autores principales: | , |
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| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
1975
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/146061 |
| Aporte de: |
| id |
I19-R120-10915-146061 |
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| record_format |
dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Bioquímica Desaturation of acids Human liver microsomes |
| spellingShingle |
Bioquímica Desaturation of acids Human liver microsomes Tacconi de Gómez Dumm, Irma Nelva Brenner, Rodolfo Roberto Oxidative desaturation of α-linolenic, linoleic, and stearic acids by human liver microsomes |
| topic_facet |
Bioquímica Desaturation of acids Human liver microsomes |
| description |
The desaturation of stearic, linoleic, and α-linolenic acids by human liver microsomes were studied. The microsomes were isolated from liver biopsies obtained during operations. It was shown that human liver microsomes are able to desaturate 1-¹⁴C-α-linolenic acid to octadeca-6,9,12,15-tetraenoic acid; 1-¹⁴C-linoleic acid to γ-linolenic acid; and 1-¹⁴C-stearic acid to oleic acid in the same system described in the rat. However, the desaturation activity obtained was low compared to other mammals. This effect was attributed to fasting, premedication, or the anaesthesia. |
| format |
Articulo Articulo |
| author |
Tacconi de Gómez Dumm, Irma Nelva Brenner, Rodolfo Roberto |
| author_facet |
Tacconi de Gómez Dumm, Irma Nelva Brenner, Rodolfo Roberto |
| author_sort |
Tacconi de Gómez Dumm, Irma Nelva |
| title |
Oxidative desaturation of α-linolenic, linoleic, and stearic acids by human liver microsomes |
| title_short |
Oxidative desaturation of α-linolenic, linoleic, and stearic acids by human liver microsomes |
| title_full |
Oxidative desaturation of α-linolenic, linoleic, and stearic acids by human liver microsomes |
| title_fullStr |
Oxidative desaturation of α-linolenic, linoleic, and stearic acids by human liver microsomes |
| title_full_unstemmed |
Oxidative desaturation of α-linolenic, linoleic, and stearic acids by human liver microsomes |
| title_sort |
oxidative desaturation of α-linolenic, linoleic, and stearic acids by human liver microsomes |
| publishDate |
1975 |
| url |
http://sedici.unlp.edu.ar/handle/10915/146061 |
| work_keys_str_mv |
AT tacconidegomezdummirmanelva oxidativedesaturationofalinoleniclinoleicandstearicacidsbyhumanlivermicrosomes AT brennerrodolforoberto oxidativedesaturationofalinoleniclinoleicandstearicacidsbyhumanlivermicrosomes |
| bdutipo_str |
Repositorios |
| _version_ |
1764820460507234306 |