Bis(oxalato)dioxovanadate(V) and bis(oxalato)oxoperoxo-vanadate(V) complexes: spectroscopic characterization and biological activity

Two structurally related vanadium(V) complexes, K3[VO2(C2O4)2]·3H2O and K3[VO(O2)(C2O4)2]·1/2H2O, were thoroughly characterized by infrared, Raman, and electronic spectroscopies. The effect of both complexes on the viability of the human MG-63 osteosarcoma cells was tested using the MTT assay. The m...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: León, Ignacio Esteban, Etcheverry, Susana Beatriz, Parajón Costa, Beatriz Susana, Baran, Enrique José
Formato: Articulo
Lenguaje:Inglés
Publicado: 2013
Materias:
Química
Vanadium(V)
Bis(oxalato) complexes
Peroxo ligand
Vibrational spectra
Electronic spectra
Osteosarcoma cells in culture
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/145349
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-145349
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Química
Vanadium(V)
Bis(oxalato) complexes
Peroxo ligand
Vibrational spectra
Electronic spectra
Osteosarcoma cells in culture
spellingShingle Química
Vanadium(V)
Bis(oxalato) complexes
Peroxo ligand
Vibrational spectra
Electronic spectra
Osteosarcoma cells in culture
León, Ignacio Esteban
Etcheverry, Susana Beatriz
Parajón Costa, Beatriz Susana
Baran, Enrique José
Bis(oxalato)dioxovanadate(V) and bis(oxalato)oxoperoxo-vanadate(V) complexes: spectroscopic characterization and biological activity
topic_facet Química
Vanadium(V)
Bis(oxalato) complexes
Peroxo ligand
Vibrational spectra
Electronic spectra
Osteosarcoma cells in culture
description Two structurally related vanadium(V) complexes, K3[VO2(C2O4)2]·3H2O and K3[VO(O2)(C2O4)2]·1/2H2O, were thoroughly characterized by infrared, Raman, and electronic spectroscopies. The effect of both complexes on the viability of the human MG-63 osteosarcoma cells was tested using the MTT assay. The monoperoxo complex shows a very strong antiproliferative activity (at 100-μM concentration, this complex diminished the cell viability ca. 80 %), whereas the dioxo complex was inactive.
format Articulo
Articulo
author León, Ignacio Esteban
Etcheverry, Susana Beatriz
Parajón Costa, Beatriz Susana
Baran, Enrique José
author_facet León, Ignacio Esteban
Etcheverry, Susana Beatriz
Parajón Costa, Beatriz Susana
Baran, Enrique José
author_sort León, Ignacio Esteban
title Bis(oxalato)dioxovanadate(V) and bis(oxalato)oxoperoxo-vanadate(V) complexes: spectroscopic characterization and biological activity
title_short Bis(oxalato)dioxovanadate(V) and bis(oxalato)oxoperoxo-vanadate(V) complexes: spectroscopic characterization and biological activity
title_full Bis(oxalato)dioxovanadate(V) and bis(oxalato)oxoperoxo-vanadate(V) complexes: spectroscopic characterization and biological activity
title_fullStr Bis(oxalato)dioxovanadate(V) and bis(oxalato)oxoperoxo-vanadate(V) complexes: spectroscopic characterization and biological activity
title_full_unstemmed Bis(oxalato)dioxovanadate(V) and bis(oxalato)oxoperoxo-vanadate(V) complexes: spectroscopic characterization and biological activity
title_sort bis(oxalato)dioxovanadate(v) and bis(oxalato)oxoperoxo-vanadate(v) complexes: spectroscopic characterization and biological activity
publishDate 2013
url http://sedici.unlp.edu.ar/handle/10915/145349
work_keys_str_mv AT leonignacioesteban bisoxalatodioxovanadatevandbisoxalatooxoperoxovanadatevcomplexesspectroscopiccharacterizationandbiologicalactivity
AT etcheverrysusanabeatriz bisoxalatodioxovanadatevandbisoxalatooxoperoxovanadatevcomplexesspectroscopiccharacterizationandbiologicalactivity
AT parajoncostabeatrizsusana bisoxalatodioxovanadatevandbisoxalatooxoperoxovanadatevcomplexesspectroscopiccharacterizationandbiologicalactivity
AT baranenriquejose bisoxalatodioxovanadatevandbisoxalatooxoperoxovanadatevcomplexesspectroscopiccharacterizationandbiologicalactivity
bdutipo_str Repositorios
_version_ 1764820460533448705

Ejemplares similares