A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep

The resulting serum concentrations were measured in six ewes after intramuscular administration of 10 mg/kg of gentamicin. The model providing the best fit for the experimental data was determined both by linear regression analysis between the experimental and theoretical values and by means of the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Errecalde, Jorge Oscar, Mariño, Eduardo L.
Formato: Articulo
Lenguaje:Inglés
Publicado: 1990
Materias:
Ciencias Veterinarias
Gentamicin
Models
Pharmacokinetics
Sheep
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/143250
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-143250
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Gentamicin
Models
Pharmacokinetics
Sheep
spellingShingle Ciencias Veterinarias
Gentamicin
Models
Pharmacokinetics
Sheep
Errecalde, Jorge Oscar
Mariño, Eduardo L.
A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
topic_facet Ciencias Veterinarias
Gentamicin
Models
Pharmacokinetics
Sheep
description The resulting serum concentrations were measured in six ewes after intramuscular administration of 10 mg/kg of gentamicin. The model providing the best fit for the experimental data was determined both by linear regression analysis between the experimental and theoretical values and by means of the Minimum Akaike Information Criterion Estimation (MAICE) test. Linear regression analysis showed certain differences favouring the monocompartmental model although the advantage was not conclusive. The MAICE test, however, permitted a clear discrimination in favour of the same model. When linear regression analysis is not conclusive, the MAICE test represents a good alternative.
format Articulo
Articulo
author Errecalde, Jorge Oscar
Mariño, Eduardo L.
author_facet Errecalde, Jorge Oscar
Mariño, Eduardo L.
author_sort Errecalde, Jorge Oscar
title A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
title_short A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
title_full A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
title_fullStr A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
title_full_unstemmed A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
title_sort discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
publishDate 1990
url http://sedici.unlp.edu.ar/handle/10915/143250
work_keys_str_mv AT errecaldejorgeoscar adiscriminatorystudyofapharmacokineticmodelforintramusculargentamicininsheep
AT marinoeduardol adiscriminatorystudyofapharmacokineticmodelforintramusculargentamicininsheep
AT errecaldejorgeoscar discriminatorystudyofapharmacokineticmodelforintramusculargentamicininsheep
AT marinoeduardol discriminatorystudyofapharmacokineticmodelforintramusculargentamicininsheep
bdutipo_str Repositorios
_version_ 1764820459777425408

Ejemplares similares