The activating effect of dietary protein on linoleic acid desaturation

The desaturation of14C-1-linoleic acid to γ-linolenic acid and their incorporation into the microsomal lipids of rats fed on a balanced diet and a protein diet were measured in vitro. It was shown that a protein diet does not change significantly the distribution of the radioactivity among the diffe...

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Autores principales: Peluffo, Raúl Omar, Tacconi de Gómez Dumm, Irma Nelva, Brenner, Rodolfo Roberto
Formato: Articulo
Lenguaje:Inglés
Publicado: 1972
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/141539
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id I19-R120-10915-141539
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Exactas
Medicina
γ-linolenic acid
14C-l-linoleic acid
microsomes
diet
spellingShingle Ciencias Exactas
Medicina
γ-linolenic acid
14C-l-linoleic acid
microsomes
diet
Peluffo, Raúl Omar
Tacconi de Gómez Dumm, Irma Nelva
Brenner, Rodolfo Roberto
The activating effect of dietary protein on linoleic acid desaturation
topic_facet Ciencias Exactas
Medicina
γ-linolenic acid
14C-l-linoleic acid
microsomes
diet
description The desaturation of14C-1-linoleic acid to γ-linolenic acid and their incorporation into the microsomal lipids of rats fed on a balanced diet and a protein diet were measured in vitro. It was shown that a protein diet does not change significantly the distribution of the radioactivity among the different lipidic fractions compared to the animals fed on a balanced diet. However the microsomal desaturation of linoleic acid to γ-linolenic acid increased in the rats maintained on a protein diet. Besides, the amount and composition of the free fatty acids present in the microsomes of the animals fed on both diets were similar enough to discard the hypothesis that they may modify the desaturation of linoleic acid produced by the diet. The enzymic activity of the linoleyl desaturase of liver microsomes of animals fed on a protein diet, measured in substrate saturating conditions, is greater than in animals with balanced diet. Consequently the results support the hypothesis that a protein diet increases specifically the desaturating activity of the microsomes.
format Articulo
Articulo
author Peluffo, Raúl Omar
Tacconi de Gómez Dumm, Irma Nelva
Brenner, Rodolfo Roberto
author_facet Peluffo, Raúl Omar
Tacconi de Gómez Dumm, Irma Nelva
Brenner, Rodolfo Roberto
author_sort Peluffo, Raúl Omar
title The activating effect of dietary protein on linoleic acid desaturation
title_short The activating effect of dietary protein on linoleic acid desaturation
title_full The activating effect of dietary protein on linoleic acid desaturation
title_fullStr The activating effect of dietary protein on linoleic acid desaturation
title_full_unstemmed The activating effect of dietary protein on linoleic acid desaturation
title_sort activating effect of dietary protein on linoleic acid desaturation
publishDate 1972
url http://sedici.unlp.edu.ar/handle/10915/141539
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