Ultrastructure of STH cells of the pars distalis of hepatectomized mice

An electron microscopic analysis was performed on the pars distalis of the hypophysis of hepatectomized mice. Intact and sham operated mice served as controls. The STH cells presented striking changes that were most intense and widespread in those animals sacrificed at midnight of the second day aft...

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Autores principales: Echave Llanos, Julián Miguel, Gómez Dumm, César Leandro Alberto, Nessi, A. C
Formato: Articulo
Lenguaje:Inglés
Publicado: 1971
Materias:
Ciencias Médicas
Pars distalis
STH cells
Hepatectomy
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/139786
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-139786
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
Pars distalis
STH cells
Hepatectomy
spellingShingle Ciencias Médicas
Pars distalis
STH cells
Hepatectomy
Echave Llanos, Julián Miguel
Gómez Dumm, César Leandro Alberto
Nessi, A. C
Ultrastructure of STH cells of the pars distalis of hepatectomized mice
topic_facet Ciencias Médicas
Pars distalis
STH cells
Hepatectomy
description An electron microscopic analysis was performed on the pars distalis of the hypophysis of hepatectomized mice. Intact and sham operated mice served as controls. The STH cells presented striking changes that were most intense and widespread in those animals sacrificed at midnight of the second day after hepatectomy. These changes can be summarized as follows: 1) Hypertrophy of the Golgi complex with increased number of immature granules within the Golgi zone. This change appeared also in otherwise unmodified STH cells. 2) Strong dilatation of the endoplasmic reticulum whose cisternae contained much electron dense material. 3) Granules with partially diminished electron density, some of them in spatial relation with the plasma membrane and others swelling and bursting within the cytoplasm. All transitions between unchanged 350–400 mμ granules and extremely altered ones, were seen. 4) Release sites, characterized by dense zones in the plasmalemma, close to aggregates of electron lucent microvesicles, and almost empty granule membranes. 5) Increase in the density of the mitochondria which appeared grouped near the Golgi zone. 6) Increase in the number of large lysosomes of the autophagic vacuole type. 7) Irregular nuclear outlines. These data suggest increased synthesis and release of growth hormone in STH cells stimulated by hepatectomy.
format Articulo
Articulo
author Echave Llanos, Julián Miguel
Gómez Dumm, César Leandro Alberto
Nessi, A. C
author_facet Echave Llanos, Julián Miguel
Gómez Dumm, César Leandro Alberto
Nessi, A. C
author_sort Echave Llanos, Julián Miguel
title Ultrastructure of STH cells of the pars distalis of hepatectomized mice
title_short Ultrastructure of STH cells of the pars distalis of hepatectomized mice
title_full Ultrastructure of STH cells of the pars distalis of hepatectomized mice
title_fullStr Ultrastructure of STH cells of the pars distalis of hepatectomized mice
title_full_unstemmed Ultrastructure of STH cells of the pars distalis of hepatectomized mice
title_sort ultrastructure of sth cells of the pars distalis of hepatectomized mice
publishDate 1971
url http://sedici.unlp.edu.ar/handle/10915/139786
work_keys_str_mv AT echavellanosjulianmiguel ultrastructureofsthcellsoftheparsdistalisofhepatectomizedmice
AT gomezdummcesarleandroalberto ultrastructureofsthcellsoftheparsdistalisofhepatectomizedmice
AT nessiac ultrastructureofsthcellsoftheparsdistalisofhepatectomizedmice
bdutipo_str Repositorios
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