Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas

1-(Acyl/aroyl)-3-(substituted)thioureas are privileged architectures that have received remarkable attention of researchers in view of their variable topological aspects, binding modes and broad spectrum promising pharmacological properties. Reactivity of acyl thiourea derivatives has presented vari...

Descripción completa

Detalles Bibliográficos
Autores principales: Saeed, Aamer, Qamar, Rabia, Fattah, Tanzeela Abdul, Flörke, Ulrich, Erben, Mauricio Federico
Formato: Articulo
Lenguaje:Inglés
Publicado: 2017
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/139410
Aporte de:
id I19-R120-10915-139410
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Química
Acyl thiourea
Ion sensors
Electronics
Corrosion
Medicinal
spellingShingle Química
Acyl thiourea
Ion sensors
Electronics
Corrosion
Medicinal
Saeed, Aamer
Qamar, Rabia
Fattah, Tanzeela Abdul
Flörke, Ulrich
Erben, Mauricio Federico
Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas
topic_facet Química
Acyl thiourea
Ion sensors
Electronics
Corrosion
Medicinal
description 1-(Acyl/aroyl)-3-(substituted)thioureas are privileged architectures that have received remarkable attention of researchers in view of their variable topological aspects, binding modes and broad spectrum promising pharmacological properties. Reactivity of acyl thiourea derivatives has presented various organic transformations into other demanding scaffolds and this is an attractive strategy for synthetic chemists to access heterocyclic cores. Multiple binding sites make them flexible ligands for complexation with transition metals thus occupying a distinct position in coordination chemistry. 1-(Acyl/aroyl)-3-(substituted)thioureas have also emerged as attractive candidates in various fields such as ion sensors, corrosion inhibitors, molecular electronics, in metal extraction and in pharmaceuticals. The medicinal chemistry of this organo-sulfur framework and the derived metal complexes has witnessed fantastic progress in the current era. In continuation of our efforts to compile data on the structural aspects and numerous applications of 1-(acyl/aroyl)-3-(substituted)thiourea analogs, continuous advances have prompted us to present an overview of the last 2 years literature on this exciting family of compounds through this review article.
format Articulo
Articulo
author Saeed, Aamer
Qamar, Rabia
Fattah, Tanzeela Abdul
Flörke, Ulrich
Erben, Mauricio Federico
author_facet Saeed, Aamer
Qamar, Rabia
Fattah, Tanzeela Abdul
Flörke, Ulrich
Erben, Mauricio Federico
author_sort Saeed, Aamer
title Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas
title_short Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas
title_full Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas
title_fullStr Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas
title_full_unstemmed Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas
title_sort recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas
publishDate 2017
url http://sedici.unlp.edu.ar/handle/10915/139410
work_keys_str_mv AT saeedaamer recentdevelopmentsinchemistrycoordinationstructureandbiologicalaspectsof1acylaroyl3substitutedthioureas
AT qamarrabia recentdevelopmentsinchemistrycoordinationstructureandbiologicalaspectsof1acylaroyl3substitutedthioureas
AT fattahtanzeelaabdul recentdevelopmentsinchemistrycoordinationstructureandbiologicalaspectsof1acylaroyl3substitutedthioureas
AT florkeulrich recentdevelopmentsinchemistrycoordinationstructureandbiologicalaspectsof1acylaroyl3substitutedthioureas
AT erbenmauriciofederico recentdevelopmentsinchemistrycoordinationstructureandbiologicalaspectsof1acylaroyl3substitutedthioureas
bdutipo_str Repositorios
_version_ 1764820457691807746