Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride

Aneuploidy is a numerical chromosomal disorder originated from nondisjunction during cell division (Dellarco 1985). Aneuploid cells exhibit altered chromosome numbers varying from nulisomy (absence of a chromosome pair), monosomy (only one member of a chromosome pair), trisomy (three homologous chro...

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Autores principales: Seoane, Analía Isabel, Dulout, Fernando Noel
Formato: Articulo
Lenguaje:Inglés
Publicado: 1994
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/139185
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id I19-R120-10915-139185
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Veterinaria
Aneuploidy
Propionaldehyde
Cadmium Chloride
spellingShingle Veterinaria
Aneuploidy
Propionaldehyde
Cadmium Chloride
Seoane, Analía Isabel
Dulout, Fernando Noel
Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride
topic_facet Veterinaria
Aneuploidy
Propionaldehyde
Cadmium Chloride
description Aneuploidy is a numerical chromosomal disorder originated from nondisjunction during cell division (Dellarco 1985). Aneuploid cells exhibit altered chromosome numbers varying from nulisomy (absence of a chromosome pair), monosomy (only one member of a chromosome pair), trisomy (three homologous chromosomes instead of two), tetrasomy (four homologous chromosomes instead of two), etc. In an aneuploid complement, one or more chromosome pairs can be involved. In human beings aneuploidy is the main cause of pregnant loss, congenital malformation and mental retard (Hook 1983; Epstein 1988). Although the consequences of meiotic non-disjunction are clear, the relation between mitotic non-disjunction and neoplastic transformation susbsists uncertain despite there is increased evidence indicating that it is a significant factor during somatic malignancy development (Kondo 1984; Tsutsui 1983; Cavenee 1983). In addition, aneuploidy is frequently associated with infertility and abortion in domestic livestock (Halnan 1989). <i>(Párrafo extraído del texto a modo de resumen)</i>
format Articulo
Articulo
author Seoane, Analía Isabel
Dulout, Fernando Noel
author_facet Seoane, Analía Isabel
Dulout, Fernando Noel
author_sort Seoane, Analía Isabel
title Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride
title_short Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride
title_full Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride
title_fullStr Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride
title_full_unstemmed Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride
title_sort use of the anaphase-telophase test to detect aneugenic compounds : effects of propionaldehyde and cadmium chloride
publishDate 1994
url http://sedici.unlp.edu.ar/handle/10915/139185
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AT duloutfernandonoel useoftheanaphasetelophasetesttodetectaneugeniccompoundseffectsofpropionaldehydeandcadmiumchloride
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