Strategies for the treatment of dairy cows at high risk for postpartum metritis and for the treatment of clinical endometritis in Argentina

The objectives of this study were to evaluate the efficacy of (1) administering ceftiofur hydrochloride in dairy cows with calving-related disorders to prevent metritis and (2) a combination of GnRH and PGF<sub>2α</sub> for the treatment of clinical endometritis, under Argentinean dairy...

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Autores principales: Bartolome, Julian A., Khalloub, Pablo, Sota, Rodolfo Luzbel de la, Drillich, Marc, Melendez, Pedro G.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2014
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/136516
Aporte de:
id I19-R120-10915-136516
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Veterinaria
Calving-related disorder
Uterine infection
Treatment
Fertility
Dairy cows
spellingShingle Veterinaria
Calving-related disorder
Uterine infection
Treatment
Fertility
Dairy cows
Bartolome, Julian A.
Khalloub, Pablo
Sota, Rodolfo Luzbel de la
Drillich, Marc
Melendez, Pedro G.
Strategies for the treatment of dairy cows at high risk for postpartum metritis and for the treatment of clinical endometritis in Argentina
topic_facet Veterinaria
Calving-related disorder
Uterine infection
Treatment
Fertility
Dairy cows
description The objectives of this study were to evaluate the efficacy of (1) administering ceftiofur hydrochloride in dairy cows with calving-related disorders to prevent metritis and (2) a combination of GnRH and PGF<sub>2α</sub> for the treatment of clinical endometritis, under Argentinean dairy farming conditions. Cows at high risk (HRC) for metritis (dystocia, RFM >12 h postpartum, hypocalcaemia, twins, or stillbirth) were randomly assigned to receive either 1.1 mg/Kg of ceftiofur hydrochloride on three consecutive days (HRC treated group HRCT, n = 110) or remained untreated (HRC control group HRCC, n = 126). Cows with low risk (LRC, no calving-related disorders, n = 868) did not receive any treatment (LRC group, n = 868). All cows were examined for metritis between days 4 and 10 and for clinical endometritis between 24 and 30 days postpartum. The body condition score (BCS) was recorded at both examinations. Cows with endometritis at days 24 to 30 postpartum received either 1.5 mg of D-cloprostenol (PGF; n = 129) or 100 μg of GnRH followed by D-cloprostenol after 7 days (GnRH+PGF, n = 119). There was no overall effect of treatment on the incidence of metritis or on time to pregnancy. Treatment, however, reduced the incidence of metritis in cows with high BCS (HRCT = 24.0 %, HRCC = 38.5 %) but had no effect in cows with low BCS (HRCT = 38.7 %, HRCC = 37.5 %). The proportion of pregnant cows by days in milk was greater (P<0.01) in LRC group compared with that of the HRCT and HRCC groups. No significant differences were found between groups PG and PG+GNRH. GnRH+PGF treatment, however, tended (P=0.06) to increase pregnancy rate in cows with a moderate loss of BCS (76.5 vs 65.2 %) but tended to reduce pregnancy rate (54.5 vs 76.0 %) in cows with a more pronounced loss in BCS (>0.75 points).
format Articulo
Articulo
author Bartolome, Julian A.
Khalloub, Pablo
Sota, Rodolfo Luzbel de la
Drillich, Marc
Melendez, Pedro G.
author_facet Bartolome, Julian A.
Khalloub, Pablo
Sota, Rodolfo Luzbel de la
Drillich, Marc
Melendez, Pedro G.
author_sort Bartolome, Julian A.
title Strategies for the treatment of dairy cows at high risk for postpartum metritis and for the treatment of clinical endometritis in Argentina
title_short Strategies for the treatment of dairy cows at high risk for postpartum metritis and for the treatment of clinical endometritis in Argentina
title_full Strategies for the treatment of dairy cows at high risk for postpartum metritis and for the treatment of clinical endometritis in Argentina
title_fullStr Strategies for the treatment of dairy cows at high risk for postpartum metritis and for the treatment of clinical endometritis in Argentina
title_full_unstemmed Strategies for the treatment of dairy cows at high risk for postpartum metritis and for the treatment of clinical endometritis in Argentina
title_sort strategies for the treatment of dairy cows at high risk for postpartum metritis and for the treatment of clinical endometritis in argentina
publishDate 2014
url http://sedici.unlp.edu.ar/handle/10915/136516
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