Effect of Injectable Copper and Zinc Supplementation on Weight, Hematological Parameters, and Immune Response in Pre-weaning Beef Calves

Copper (Cu) and zinc (Zn) deficiency may cause poor weight gain, hematological changes, and immune failure in extensive beef cattle breeding systems. Diagnosis of the deficiency is based on plasma Cu and Zn concentrations; however, there are discrepancies regarding data interpretation. Here, plasma...

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Autores principales: Mattioli, Guillermo Alberto, Rosa, Diana Esther, Turic, Esteban, Testa, Juan Alberto, Lizarraga, Raúl Martín, Fazzio, Luis Emilio
Formato: Articulo
Lenguaje:Inglés
Publicado: 2019
Materias:
Veterinaria
Beef cattle
Trace elements
Diagnosis
Immune response
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/135922
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-135922
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Veterinaria
Beef cattle
Trace elements
Diagnosis
Immune response
spellingShingle Veterinaria
Beef cattle
Trace elements
Diagnosis
Immune response
Mattioli, Guillermo Alberto
Rosa, Diana Esther
Turic, Esteban
Testa, Juan Alberto
Lizarraga, Raúl Martín
Fazzio, Luis Emilio
Effect of Injectable Copper and Zinc Supplementation on Weight, Hematological Parameters, and Immune Response in Pre-weaning Beef Calves
topic_facet Veterinaria
Beef cattle
Trace elements
Diagnosis
Immune response
description Copper (Cu) and zinc (Zn) deficiency may cause poor weight gain, hematological changes, and immune failure in extensive beef cattle breeding systems. Diagnosis of the deficiency is based on plasma Cu and Zn concentrations; however, there are discrepancies regarding data interpretation. Here, plasma Cu and Zn concentrations are discussed as risk markers. We evaluated the effect of parenteral Cu and Zn supplementation on their plasma concentrations, weight gain, hematological parameters, and antibody titers to bovine herpes virus 1 (BoHV-1). Pre-weaning calves (n = 40; 99 ± 8 kg bw) from a typical breeding area of Argentina with background Cu and Zn deficiency were used. They were assigned to two homogeneous groups in a completely randomized design. Calves were subcutaneously injected with 0.3 mg/kg Cu and 1 mg/kg Zn (supplemented group), or saline solution (control), every 40 days during 120 days. Plasma Cu and Zn concentrations, hematological parameters, and weight were recorded. On days 40 and 80 of the trial, calves were vaccinated with inactivated BoHV-1. Antibody immune response was measured on days 80 and 120. Data were analyzed with a mixed model for repeated measures over time. Before treatment, plasma Cu was low and Zn was adequate in both groups. After treatment, plasma Cu increased and remained within a normal range, whereas plasma Zn remained constant. Supplemented animals had higher weight gain (p < 0.01); higher hematocrit, mean corpuscular volume, and mean corpuscular hemoglobin levels (p < 0.05); and higher immune response to BoHV-1 (p < 0.05). Our results suggest that Cu and Zn supplementation improved daily weight gain and the immune response of pre-weaning calves.
format Articulo
Articulo
author Mattioli, Guillermo Alberto
Rosa, Diana Esther
Turic, Esteban
Testa, Juan Alberto
Lizarraga, Raúl Martín
Fazzio, Luis Emilio
author_facet Mattioli, Guillermo Alberto
Rosa, Diana Esther
Turic, Esteban
Testa, Juan Alberto
Lizarraga, Raúl Martín
Fazzio, Luis Emilio
author_sort Mattioli, Guillermo Alberto
title Effect of Injectable Copper and Zinc Supplementation on Weight, Hematological Parameters, and Immune Response in Pre-weaning Beef Calves
title_short Effect of Injectable Copper and Zinc Supplementation on Weight, Hematological Parameters, and Immune Response in Pre-weaning Beef Calves
title_full Effect of Injectable Copper and Zinc Supplementation on Weight, Hematological Parameters, and Immune Response in Pre-weaning Beef Calves
title_fullStr Effect of Injectable Copper and Zinc Supplementation on Weight, Hematological Parameters, and Immune Response in Pre-weaning Beef Calves
title_full_unstemmed Effect of Injectable Copper and Zinc Supplementation on Weight, Hematological Parameters, and Immune Response in Pre-weaning Beef Calves
title_sort effect of injectable copper and zinc supplementation on weight, hematological parameters, and immune response in pre-weaning beef calves
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/135922
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