Presence of binucleate neurons in the spinal cord of young and senile rats

The presence of binucleate cells constitutes a normal feature of some animal tissues but is rare in the normal brain and has not been documented in the spinal cord. We assessed different segments of the rat spinal cord in order to determine the frequency and distribution of binucleate neurons in thi...

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Autores principales: Portiansky, Enrique Leo, Barbeito, Claudio Gustavo, Flamini, Mirta Alicia, Gimeno, Eduardo Juan, Goya, Rodolfo Gustavo
Formato: Articulo Contribucion a revista
Lenguaje:Inglés
Publicado: 2006
Materias:
Ciencias Veterinarias
Veterinaria
Spinal cord
Binucleate neurons
Cell counting
Morphology
Aging
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/133664
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-133664
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Veterinaria
Spinal cord
Binucleate neurons
Cell counting
Morphology
Aging
spellingShingle Ciencias Veterinarias
Veterinaria
Spinal cord
Binucleate neurons
Cell counting
Morphology
Aging
Portiansky, Enrique Leo
Barbeito, Claudio Gustavo
Flamini, Mirta Alicia
Gimeno, Eduardo Juan
Goya, Rodolfo Gustavo
Presence of binucleate neurons in the spinal cord of young and senile rats
topic_facet Ciencias Veterinarias
Veterinaria
Spinal cord
Binucleate neurons
Cell counting
Morphology
Aging
description The presence of binucleate cells constitutes a normal feature of some animal tissues but is rare in the normal brain and has not been documented in the spinal cord. We assessed different segments of the rat spinal cord in order to determine the frequency and distribution of binucleate neurons in this structure as well as the impact of aging on this neuronal population. Young (4–5 months) and senile (32 months) female Sprague–Dawley rats were used. Sections from cervical, thoracic and lumbar segments were histochemically and immunohistochemically (NeuN) stained and the frequency and distribution of binucleate neurons was determined by manual counting. The frequency of binucleate neurons in all of the analysed segments was comparable between young and senile animals. Binucleate neurons were particularly frequent in the C5 and C6 segments. The overall distribution of binucleate neurons in the different laminae assessed was, Lm-III = 19%; Lm-VI = 17%; Lm-VII = 39%; LmVIII = 8%; Lm-IX = 11%; Lm-X = 6%, and was comparable between young and senile rats. We conclude that binucleate neurons occur as a normal feature of the rat spinal cord and that their frequency and distribution does not change with aging.
format Articulo
Contribucion a revista
author Portiansky, Enrique Leo
Barbeito, Claudio Gustavo
Flamini, Mirta Alicia
Gimeno, Eduardo Juan
Goya, Rodolfo Gustavo
author_facet Portiansky, Enrique Leo
Barbeito, Claudio Gustavo
Flamini, Mirta Alicia
Gimeno, Eduardo Juan
Goya, Rodolfo Gustavo
author_sort Portiansky, Enrique Leo
title Presence of binucleate neurons in the spinal cord of young and senile rats
title_short Presence of binucleate neurons in the spinal cord of young and senile rats
title_full Presence of binucleate neurons in the spinal cord of young and senile rats
title_fullStr Presence of binucleate neurons in the spinal cord of young and senile rats
title_full_unstemmed Presence of binucleate neurons in the spinal cord of young and senile rats
title_sort presence of binucleate neurons in the spinal cord of young and senile rats
publishDate 2006
url http://sedici.unlp.edu.ar/handle/10915/133664
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