Broken Rice as a Potential Functional Ingredient with Inhibitory Activity of Renin and Angiotensin-Converting Enzyme(ACE)

The aim of this work was to evaluate the ability of broken rice, an underutilized industrial by-product, as a potential functional and health promoting ingredient. With this purpose, the ability to inhibit the angiotensin converting enzyme and renin of a rice protein hydrolyzate (RPH) obtained from...

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Autores principales: Pinciroli, María, Aphalo, Paula, Nardo, Agustina Estefanía, Añón, María Cristina, Quiroga, Alejandra Viviana
Formato: Articulo
Lenguaje:Inglés
Publicado: 2019
Materias:
Ciencias Agrarias
Biología
Broken rice
ACE inhibitory peptides
Renin inhibitory peptides
Molecular docking analysis
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/133371
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-133371
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Agrarias
Biología
Broken rice
ACE inhibitory peptides
Renin inhibitory peptides
Molecular docking analysis
spellingShingle Ciencias Agrarias
Biología
Broken rice
ACE inhibitory peptides
Renin inhibitory peptides
Molecular docking analysis
Pinciroli, María
Aphalo, Paula
Nardo, Agustina Estefanía
Añón, María Cristina
Quiroga, Alejandra Viviana
Broken Rice as a Potential Functional Ingredient with Inhibitory Activity of Renin and Angiotensin-Converting Enzyme(ACE)
topic_facet Ciencias Agrarias
Biología
Broken rice
ACE inhibitory peptides
Renin inhibitory peptides
Molecular docking analysis
description The aim of this work was to evaluate the ability of broken rice, an underutilized industrial by-product, as a potential functional and health promoting ingredient. With this purpose, the ability to inhibit the angiotensin converting enzyme and renin of a rice protein hydrolyzate (RPH) obtained from a high-protein variety of broken rice (var. Nutriar FCAyF) was analyzed (IC₅₀ = 0.87 and 2.7 mg/mL, respectively). RPH was separated by gel permeation chromatography and in a second purification step by RP-HPLC. The sequence of antihypertensive peptides presented in two RP-HPLC fractions was analyzed. Peptides capable of interacting with the active sites of both enzymes were identified. In this study, we demonstrate that the hydrolysis treatment improves functional and biological properties of rice proteins. Protein preparations obtained from a by-product of rice industry, such as broken rice, are a promising ingredient with potentially good biological properties.
format Articulo
Articulo
author Pinciroli, María
Aphalo, Paula
Nardo, Agustina Estefanía
Añón, María Cristina
Quiroga, Alejandra Viviana
author_facet Pinciroli, María
Aphalo, Paula
Nardo, Agustina Estefanía
Añón, María Cristina
Quiroga, Alejandra Viviana
author_sort Pinciroli, María
title Broken Rice as a Potential Functional Ingredient with Inhibitory Activity of Renin and Angiotensin-Converting Enzyme(ACE)
title_short Broken Rice as a Potential Functional Ingredient with Inhibitory Activity of Renin and Angiotensin-Converting Enzyme(ACE)
title_full Broken Rice as a Potential Functional Ingredient with Inhibitory Activity of Renin and Angiotensin-Converting Enzyme(ACE)
title_fullStr Broken Rice as a Potential Functional Ingredient with Inhibitory Activity of Renin and Angiotensin-Converting Enzyme(ACE)
title_full_unstemmed Broken Rice as a Potential Functional Ingredient with Inhibitory Activity of Renin and Angiotensin-Converting Enzyme(ACE)
title_sort broken rice as a potential functional ingredient with inhibitory activity of renin and angiotensin-converting enzyme(ace)
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/133371
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