A spectrophotometric study of the VO2+-glutathione interactions

The interaction of the vanadyl (IV) cation with reduced glutathione (GSH) has been investigated by electronic absorption spectroscopy, at different metal-to-ligand ratios and pH values. The interaction depends strongly on the initial VO2+/GSH ratio. Starting with a tenfold GSH excess, coordination t...

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Autores principales: Ferrer, Evelina Gloria, Williams, Patricia Ana María, Baran, Enrique José
Formato: Articulo
Lenguaje:Inglés
Publicado: 1991
Materias:
Química
Vanadyl(IV)-reduced glutathione complexes
effect of the metal-to-ligand ratios
vanadyl(IV) interactions with glycine
L-cysteine, and L-glutamic acid
vanadate(V)-reduced-glutathione interactions
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/132858
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-132858
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Química
Vanadyl(IV)-reduced glutathione complexes
effect of the metal-to-ligand ratios
vanadyl(IV) interactions with glycine
L-cysteine, and L-glutamic acid
vanadate(V)-reduced-glutathione interactions
spellingShingle Química
Vanadyl(IV)-reduced glutathione complexes
effect of the metal-to-ligand ratios
vanadyl(IV) interactions with glycine
L-cysteine, and L-glutamic acid
vanadate(V)-reduced-glutathione interactions
Ferrer, Evelina Gloria
Williams, Patricia Ana María
Baran, Enrique José
A spectrophotometric study of the VO2+-glutathione interactions
topic_facet Química
Vanadyl(IV)-reduced glutathione complexes
effect of the metal-to-ligand ratios
vanadyl(IV) interactions with glycine
L-cysteine, and L-glutamic acid
vanadate(V)-reduced-glutathione interactions
description The interaction of the vanadyl (IV) cation with reduced glutathione (GSH) has been investigated by electronic absorption spectroscopy, at different metal-to-ligand ratios and pH values. The interaction depends strongly on the initial VO2+/GSH ratio. Starting with a tenfold GSH excess, coordination takes place through the two carboxylate groups of the ligand, generating (at pH=7) a blue 1∶2 VO2+/GSH complex; this stoichiometry could be confirmed by photometric titration experiments. Higher GSH concentrations produce a violet complex, which can also be obtained by addition of GSH to the blue species. Some measurements with the three component amino acids of GSH, as well as results obtained from the VO3−/GSH system, allowed a wider insight into the characteristics of this violet complex, in which the cation interacts with S and N atoms of the peptide.
format Articulo
Articulo
author Ferrer, Evelina Gloria
Williams, Patricia Ana María
Baran, Enrique José
author_facet Ferrer, Evelina Gloria
Williams, Patricia Ana María
Baran, Enrique José
author_sort Ferrer, Evelina Gloria
title A spectrophotometric study of the VO2+-glutathione interactions
title_short A spectrophotometric study of the VO2+-glutathione interactions
title_full A spectrophotometric study of the VO2+-glutathione interactions
title_fullStr A spectrophotometric study of the VO2+-glutathione interactions
title_full_unstemmed A spectrophotometric study of the VO2+-glutathione interactions
title_sort spectrophotometric study of the vo2+-glutathione interactions
publishDate 1991
url http://sedici.unlp.edu.ar/handle/10915/132858
work_keys_str_mv AT ferrerevelinagloria aspectrophotometricstudyofthevo2glutathioneinteractions
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AT baranenriquejose aspectrophotometricstudyofthevo2glutathioneinteractions
AT ferrerevelinagloria spectrophotometricstudyofthevo2glutathioneinteractions
AT williamspatriciaanamaria spectrophotometricstudyofthevo2glutathioneinteractions
AT baranenriquejose spectrophotometricstudyofthevo2glutathioneinteractions
bdutipo_str Repositorios
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